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This gene encodes a protein belonging to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. This family member is most abundant in muscle but is expressed in all tissues.
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Protein Aliases: 4'-phosphopantetheine phosphatase; DKFZp547M242; FLJ10782; hPanK4; hypothetical protein Fang1; Inactive pantothenic acid kinase 4; mPanK4; pantothenate kinase 4; pantothenic acid kinase 4; rPanK4
Gene Aliases: D030031I12Rik; Fang1; PANK4; R75150
UniProt ID: (Human) Q9NVE7, (Mouse) Q80YV4, (Rat) Q923S8
Entrez Gene ID: (Human) 55229, (Mouse) 269614, (Rat) 171053
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