Proteintech

PAPSS1 Polyclonal Antibody

PAPSS1 Antibody in Immunocytochemistry (ICC/IF)

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PAPSS1 Antibody (14708-1-AP) in ICC/IF

Immunofluorescent analysis of (10% Formaldehyde) fixed HepG2 cells using 14708-1-AP (PAPSS1 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

PAPSS1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

PAPSS1 Antibody in Immunoprecipitation (IP)

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Product Details

14708-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 1 publication 1 publication

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

1:20-1:200

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

PAPSS1 Fusion Protein Ag6401 (1-624 aa encoded by BC050627)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.28 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MEIPGSLCK KVKLSNNAQN WGMQRATNVT YQAHHVSRNK RGQVVGTRGG FRGCTVWLTG LSGAGKTTVS MALEEYLVCH GIPCYTLDGD NIRQGLNKNL GFSPEDREEN VRRIAEVAKL FADAGLVCIT SFISPYTQDR NNARQIHEGA SLPFFEVFVD APLHVCEQRD VKGLYKKARA GEIKGFTGID SEYEKPEAPE LVLKTDSCDV NDCVQQVVEL LQERDIVPVD ASYEVKELYV PENKLHLAKT DAETLPALKI NKVDMQWVQV LAEGWATPLN GFMREREYLQ CLHFDCLLDG GVINLSVPIV LTATHEDKER LDGCTAFALM YEGRRVAILR NPEFFEHRKE ERCARQWGTT CKNHPYIKMV MEQGDWLIGG DLQVLDRVYW NDGLDQYRLT PTELKQKFKD MNADAVFAFQ LRNPVHNGHA LLMQDTHKQL LERGYRRPVL LLHPLGGWTK DDDVPLMWRM KQHAAVLEEG VLNPETTVVA IFPSPMMYAG PTEVQWHCRA RMVAGANFYI VGRDPAGMPH PETGKDLYEP SHGAKVLTMA PGLITLEIVP FRVAAYNKKK KRMDYYDSEH HEDFEFISGT RMRKLAREGQ KPPEGFMAPK AWTVLTEYYK SLEKA (1-624 aa encoded by BC050627)

Target Information

Three-prime-phosphoadenosine 5-prime-phosphosulfate (PAPS) is the sulfate donor cosubstrate for all sulfotransferase (SULT) enzymes (Xu et al., 2000 ). SULTs catalyze the sulfate conjugation of many endogenous and exogenous compounds, including drugs and other xenobiotics. In humans, PAPS is synthesized from adenosine 5-prime triphosphate (ATP) and inorganic sulfate by 2 isoforms, PAPSS1 and PAPSS2.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Correlation of 3'-phosphoadenosine-5'-phosphosulfate synthase 1 (PAPSS1) expression with clinical parameters and prognosis in esophageal squamous cell carcinoma.

Histology and histopathology

Zhu X,Zhu P,Chen X,Zhang L,Wu C,Zhang H,Shen X,Qi Y,Chen M,Wang S,Yi X

Wed Nov 01 00:00:00 UTC 2023

Modulating tyrosine sulfation of recombinant antibodies in CHO cell culture by host selection and sodium chlorate supplementation.

Biotechnology journal

Liu R,Zhang Y,Kumar A,Huhn S,Hullinger L,Du Z

Wed Sep 01 00:00:00 UTC 2021

CIB2 Negatively Regulates Oncogenic Signaling in Ovarian Cancer via Sphingosine Kinase 1.

Cancer research

Zhu W,Jarman KE,Lokman NA,Neubauer HA,Davies LT,Gliddon BL,Taing H,Moretti PAB,Oehler MK,Pitman MR,Pitson SM

Fri Sep 15 00:00:00 UTC 2017

CIB2 Negatively Regulates Oncogenic Signaling in Ovarian Cancer via Sphingosine Kinase 1.

Cancer research

Zhu W,Jarman KE,Lokman NA,Neubauer HA,Davies LT,Gliddon BL,Taing H,Moretti PAB,Oehler MK,Pitman MR,Pitson SM

Fri Sep 15 00:00:00 UTC 2017

CIB2 Negatively Regulates Oncogenic Signaling in Ovarian Cancer via Sphingosine Kinase 1.

Cancer research

Zhu W,Jarman KE,Lokman NA,Neubauer HA,Davies LT,Gliddon BL,Taing H,Moretti PAB,Oehler MK,Pitman MR,Pitson SM

Fri Sep 15 00:00:00 UTC 2017

CIB2 Negatively Regulates Oncogenic Signaling in Ovarian Cancer via Sphingosine Kinase 1.

Cancer research

Zhu W,Jarman KE,Lokman NA,Neubauer HA,Davies LT,Gliddon BL,Taing H,Moretti PAB,Oehler MK,Pitman MR,Pitson SM

Fri Sep 15 00:00:00 UTC 2017

Bioinformatics

Protein Aliases: 3-prime-phosphoadenosine 5-prime-phosphosulfate synthase 1; adenylyl-sulfate kinase; Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1; PAPS synthase 1; PAPS Synthetase 1; PAPSS 1; SK 1; sulfate adenylyltransferase; Sulfurylase kinase 1

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Gene Aliases: AI325286; Asapk; ATPSK1; PAPSS; PAPSS1; SK1

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UniProt ID: (Human) O43252, (Mouse) Q60967

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Entrez Gene ID: (Human) 9061, (Mouse) 23971, (Rat) 295443

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Function(s)

adenylylsulfate kinase activity sulfate adenylyltransferase (ATP) activity ATP binding nucleotidyltransferase activity nucleotide binding catalytic activity kinase activity transferase activity

Process(es)

sulfate assimilation metabolic process phosphorylation 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process skeletal system development

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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PAPSS1 Polyclonal Antibody

PAPSS1 Antibody (14708-1-AP) in ICC/IF

Product Details

14708-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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