Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji.
Predicted reactivity: Mouse (96%), Rat (96%), Xenopus laevis (88%), Rabbit (98%), Rhesus Monkey (100%), Bovine (95%), Guinea pig (95%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Sulfation is a common modification of endogenous (lipids, proteins, and carbohydrates) and exogenous (xenobiotics and drugs) compounds. In mammals, the sulfate source is 3'-phosphoadenosine 5'-phosphosulfate (PAPS), created from ATP and inorganic sulfate. Two different tissue isoforms encoded by different genes synthesize PAPS. This gene encodes one of the two PAPS synthetases. Defects in this gene cause the Pakistani type of spondyloepimetaphyseal dysplasia. Two alternatively spliced transcript variants that encode different isoforms have been described for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 3-prime-phosphoadenosine 5-prime-phosphosulfate synthase 2; adenosine 5'-phosphosulfate kinase; adenylyl-sulfate kinase; ATP sulfurylase/adenosine 5'-phosphosulfate kinase; ATP sulfurylase/APS kinase 2; Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2; bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthethase 2; PAPS synthase 2; PAPS synthetase 2; PAPS synthethase 2; SK 2; sulfate adenylyltransferase; Sulfurylase kinase 2
Gene Aliases: ATPSK2; BCYM4; PAPSS2; SK2
UniProt ID: (Human) O95340
Entrez Gene ID: (Human) 9060, (Rat) 294103
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