Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
PAR6 Polyclonal Antibody
Promotion
View available promotion(s)
Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
FIGURE: 1 / 4
PAR6 Antibody (PA3-911) in ICC/IF
Immunofluorescent analysis of Par-6 (green) showing staining in the cytoplasm of NIH-3T3 cells (right) compared to a negative control without primary antibody (left). Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with a Par-6 polyclonal antibody (Product # PA3-911) in 3% BSA-PBS at a dilution of 1:100 and incubated overnight at 4 ºC in a humidified chamber. Cells were washed with PBST and incubated with a DyLight-conju... View More
Product Details
PA3-911
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Combination of two synthetic peptides coupled to KLH.
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2283466
Product Specific Information
PA3-911detects Par-6 from human and mouse samples.
PA3-911has been successfully used in Western blot and ICC/IF procedures. This antibody is not recommended for U87-MG cells in Western blot applications.
The PA3-911 immunogen is a combination of two synthetic peptides coupled to KLH.
Target Information
This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 domain and a semi-Cdc42/Rac interactive binding domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: PAR-6; PAR-6 alpha; par-6 partitioning defective 6 homolog alpha; PAR6C; Partitioning defective 6 homolog alpha; partitioning defective-6 homolog alpha; partitioning-defective protein 6; Tax interaction protein 40; Tax-interacting protein 40; TIP-40
Gene Aliases: PAR-6A; PAR6; PAR6A; PAR6alpha; PAR6C; PARD6A; TAX40; TIP-40
UniProt ID: (Human) Q9NPB6
Entrez Gene ID: (Human) 50855
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support