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Abnova
PARD6A Polyclonal Antibody, MaxPab™
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Product Details
H00050855-D01P
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PARD6A (NP_001032358.1, 1 a.a. approximately 345 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MARPQRTPAR SPDSIVEVKS KFDAEFRRFA LPRASVSGFQ EFSRLLRAVH QIPGLDVLLG YTDAHGDLLP LTNDDSLHRA LASGPPPLRL LVQKREADSS GLAFASNSLQ RRKKGLLLRP VAPLRTRPPL LISLPQDFRQ VSSVIDVDLL PETHRRVRLH KHGSDRPLGF YIRDGMSVRV APQGLERVPG IFISRLVRGG LAESTGLLAV SDEILEVNGI EVAGKTLDQV TDMMVANSHN LIVTVKPANQ RNNVVRGASG RLTGPPSAGP GPAEPDSDDD SSDLVIENRQ PPSSNGLSQG PPCWDLHPGC RHPGTRSSLP SLDDQEQASS GWGSRIRGDG SGFSL
Target Information
This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 domain and a semi-Cdc42/Rac interactive binding domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: PAR-6; par-6 (partitioning defective 6,) homolog alpha; PAR-6 alpha; par-6 partitioning defective 6 homolog alpha; PAR6C; Partitioning defective 6 homolog alpha; partitioning defective-6 homolog alpha; partitioning-defective protein 6; Tax interaction protein 40; Tax-interacting protein 40; TIP-40
Gene Aliases: 0710008C04Rik; 2610010A15Rik; Par-6; PAR-6A; PAR6; PAR6A; PAR6alpha; PAR6C; PARD6A; TAX40; TIP-40
UniProt ID: (Human) Q9NPB6, (Mouse) Q9Z101
Entrez Gene ID: (Human) 50855, (Mouse) 56513
negative regulation of protein phosphorylation
cell cycle
transforming growth factor beta receptor signaling pathway
viral process
cell-cell junction maintenance
cell division
Wnt signaling pathway, planar cell polarity pathway
regulation of cellular localization
bicellular tight junction assembly
establishment of cell polarity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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