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This antibody detects PARD6B with an apparent molecular weight of 50-53 kDa as has been demonstrated by several researches.
Immunogen sequence: MNRSHRHGA GSGCLGTMEV KSKFGAEFRR FSLERSKPGK FEEFYGLLQH VHKIPNVDVL VGYADIHGDL LPINNDDNYH KAVSTANPLL RIFIQKKEEA DYSAFGTDTL IKKKNVLTNV LRPDNHRKKP HIVISMPQDF RPVSSIIDVD ILPETHRRVR LYKYGTEKPL GFYIRDGSSV RVTPHGLEKV PGIFISRLVP GGLAQSTGLL AVNDEVLEVN GIEVSGKSLD QVTDMMIANS RNLIITVRPA NQRNNVVRNS RTSGSSGQST DNSLLGYPQQ IEPSFEPEDE DSEEDDIIIE DNGVPQQIPK AVPNTESLES LTQIELSFES GQNGFIPSNE VSLAAIASSS NTEFETHAPD QKLLEEDGTI ITL (1-372 aa encoded by BC060847)
This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain, an OPR domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cytoplasmic protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: par-6 (partitioning defective 6) homolog beta; PAR-6 beta; par-6 partitioning defective 6 homolog beta; PAR-6B; Partitioning defective 6 homolog beta; partitioning-defective protein 6, beta
Gene Aliases: AV025615; PAR6B; PARD6B
UniProt ID: (Human) Q9BYG5, (Mouse) Q9JK83
Entrez Gene ID: (Human) 84612, (Mouse) 58220, (Rat) 362279
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