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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • PARP3 Antibodies

          Proteintech

          PARP3 Polyclonal Antibody

          2 References
          View all (12) PARP3 antibodies

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          Datasheet
          Protocols
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          Cite PARP3 Polyclonal Antibody

          • Antibody Testing Data (8)
          PARP3 Antibody in Immunocytochemistry (ICC/IF)
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          PARP3 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 8

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          PARP3 Antibody (11289-1-AP) in ICC/IF

          Immunofluorescent analysis of Hela cells, using PARP3 antibody 11289-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IGG (red). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          PARP3 Antibody in Immunocytochemistry (ICC/IF)
          PARP3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PARP3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PARP3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PARP3 Antibody in Western Blot (WB)
          PARP3 Antibody in Western Blot (WB)
          PARP3 Antibody in Western Blot (WB)
          PARP3 Antibody in Western Blot (WB)

          Product Details

          11289-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          View 2 publications 2 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:20-1:200
          -

          Immunocytochemistry (ICC/IF)

          1:10-1:100
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          PARP3 Fusion Protein Ag1844 (234-533 aa encoded by BC014260)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.22 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: EALEEALKG PTDGGQSLEE LSSHFYTVIP HNFGHSQPPP INSPELLQAK KDMLLVLADI ELAQALQAVS EQEKTVEEVP HPLDRDYQLL KCQLQLLDSG APEYKVIQTY LEQTGSNHRC PTLQHIWKVN QEGEEDRFQA HSKLGNRKLL WHGTNMAVVA AILTSGLRIM PHSGGRVGKG IYFASENSKS AGYVIGMKCG AHHVGYMFLG EVALGREHHI NTDNPSLKSP PPGFDSVIAR GHTEPDPTQD TELELDGQQV VVPQGQPVPC PEFSSSTFSQ SEYLIYQESQ CRLRYLLEVH L (234-533 aa encoded by BC014260)

          Target Information

          PARP3, poly(ADP-ribosyl)transferase 3, belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This protein is preferentially localized to the daughter centriole throughout the cell cycle.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: A DP-ribosyltransferase (NAD+; poly (ADP-ribose polymerase)-like 3; ADP-ribosyltransferase (NAD+, poly (ADP-ribose polymerase)-like 3; ADP-ribosyltransferase (NAD+; poly (ADP-ribose polymerase)-like 3; ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 2; ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 3; ADP-ribosyltransferase diphtheria toxin-like 3; ADPRT-3; ARTD3; DNA ADP-ribosyltransferase PARP3; IRT1; NAD(+) ADP-ribosyltransferase 3; NAD+ ADP-ribosyltransferase 3; pADPRT-3; PARP-3; poly (ADP-ribose) polymerase family, member 3; poly (ADP-ribosyl) transferase-like 3; Poly [ADP-ribose] polymerase 3; poly(ADP-ribose) synthetase-3; Poly[ADP-ribose] synthase 3; poly[ADP-ribose] synthetase 3; Poly[ADP-ribose] synthetase-3; Protein mono-ADP-ribosyltransferase PARP3

          View more View less

          Gene Aliases: A930002C11Rik; ADPRT3; ADPRTL2; ADPRTL3; ARTD3; AW990611; IRT1; PADPRT-3; PARP-3; PARP3

          View more View less

          UniProt ID: (Human) Q9Y6F1, (Mouse) Q3ULW8

          View more View less

          Entrez Gene ID: (Human) 10039, (Mouse) 235587, (Rat) 300985

          View more View less

          Function(s)
          catalytic activity DNA ligase (ATP) activity NAD+ ADP-ribosyltransferase activity
          Process(es)
          telomere maintenance double-strand break repair protein ADP-ribosylation positive regulation of DNA ligation regulation of mitotic spindle organization protein localization to site of double-strand break lagging strand elongation DNA repair DNA ligation involved in DNA repair
          It has to be done as per old AB suggested Products section.
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