Proteintech

PARP9 Polyclonal Antibody

PARP9 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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PARP9 Antibody (17535-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human lymphoma using 17535-1-AP (PARP9 antibody) at dilution of 1:50 (under 10x lens).

PARP9 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

17535-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 4 publications 4 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

View 2 publications 2 publications

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

PARP9 Fusion Protein Ag11587 (476-819 aa encoded by BC039580)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.33 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: EARSPAINL MGFNVEEMYE AHAWIQRILS LQNHHIIENN HILYLGRKEH DILSQLQKTS SVSITEIISP GRTELEIEGA RADLIEVVMN IEDMLCKVQE EMARKKERGL WRSLGQWTIQ QQKTQDEMKE NIIFLKCPVP PTQELLDQKK QFEKCGLQVL KVEKIDNEVL MAAFQRKKKM MEEKLHRQPV SHRLFQQVPY QFCNVVCRVG FQRMYSTPCD PKYGAGIYFT KNLKNLAEKA KKISAADKLI YVFEAEVLTG FFCQGHPLNI VPPPLSPGAI DGHDSVVDNV SSPETFVIFS GMQAIPQYLW TCTQEYVQSQ DYSSGPMRPF AQHPWRGFAS GSPVD (476-819 aa encoded by BC039580)

Target Information

In concert with DTX3L plays a role in PARP1-dependent DNA damage repair. PARP1-dependent PARP9/BAL1-DTX3L-mediated ubiquitination promotes the rapid and specific recruitment of 53BP1/TP53BP1, UIMC1/RAP80, and BRCA1 to DNA damage sites. Involved in inducing the expression of IFN-gamma-responsive genes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

An Alternative Splicing of Tupaia STING Modulated Anti-RNA Virus Responses by Targeting MDA5-LGP2 and IRF3.

Journal of immunology (Baltimore, Md. : 1950)

Xu L,Yu D,Peng L,Wu Y,Fan Y,Gu T,Yao YL,Zhong J,Chen X,Yao YG

Mon Jun 15 00:00:00 UTC 2020

An Alternative Splicing of Tupaia STING Modulated Anti-RNA Virus Responses by Targeting MDA5-LGP2 and IRF3.

Journal of immunology (Baltimore, Md. : 1950)

Xu L,Yu D,Peng L,Wu Y,Fan Y,Gu T,Yao YL,Zhong J,Chen X,Yao YG

Mon Jun 15 00:00:00 UTC 2020

Exosomes Serve as Nanoparticles to Deliver Anti-miR-214 to Reverse Chemoresistance to Cisplatin in Gastric Cancer.

Molecular therapy : the journal of the American Society of Gene Therapy

Wang X,Zhang H,Bai M,Ning T,Ge S,Deng T,Liu R,Zhang L,Ying G,Ba Y

Wed Mar 07 00:00:00 UTC 2018

Exosomes Serve as Nanoparticles to Deliver Anti-miR-214 to Reverse Chemoresistance to Cisplatin in Gastric Cancer.

Molecular therapy : the journal of the American Society of Gene Therapy

Wang X,Zhang H,Bai M,Ning T,Ge S,Deng T,Liu R,Zhang L,Ying G,Ba Y

Wed Mar 07 00:00:00 UTC 2018

PARP9 is overexpressed in human breast cancer and promotes cancer cell migration.

Oncology letters

Tang X,Zhang H,Long Y,Hua H,Jiang Y,Jing J

Sat Sep 01 00:00:00 UTC 2018

PARP9 is overexpressed in human breast cancer and promotes cancer cell migration.

Oncology letters

Tang X,Zhang H,Long Y,Hua H,Jiang Y,Jing J

Sat Sep 01 00:00:00 UTC 2018

Ubiquitin Modification by the E3 Ligase/ADP-Ribosyltransferase Dtx3L/Parp9.

Molecular cell

Yang CS,Jividen K,Spencer A,Dworak N,Ni L,Oostdyk LT,Chatterjee M,Kuśmider B,Reon B,Parlak M,Gorbunova V,Abbas T,Jeffery E,Sherman NE,Paschal BM

Thu May 18 00:00:00 UTC 2017

Ubiquitin Modification by the E3 Ligase/ADP-Ribosyltransferase Dtx3L/Parp9.

Molecular cell

Yang CS,Jividen K,Spencer A,Dworak N,Ni L,Oostdyk LT,Chatterjee M,Kuśmider B,Reon B,Parlak M,Gorbunova V,Abbas T,Jeffery E,Sherman NE,Paschal BM

Thu May 18 00:00:00 UTC 2017

Ubiquitin Modification by the E3 Ligase/ADP-Ribosyltransferase Dtx3L/Parp9.

Molecular cell

Yang CS,Jividen K,Spencer A,Dworak N,Ni L,Oostdyk LT,Chatterjee M,Kuśmider B,Reon B,Parlak M,Gorbunova V,Abbas T,Jeffery E,Sherman NE,Paschal BM

Thu May 18 00:00:00 UTC 2017

Ubiquitin Modification by the E3 Ligase/ADP-Ribosyltransferase Dtx3L/Parp9.

Molecular cell

Yang CS,Jividen K,Spencer A,Dworak N,Ni L,Oostdyk LT,Chatterjee M,Kuśmider B,Reon B,Parlak M,Gorbunova V,Abbas T,Jeffery E,Sherman NE,Paschal BM

Thu May 18 00:00:00 UTC 2017

Bioinformatics

Protein Aliases: ADP-ribosyltransferase diphtheria toxin-like 9; ARTD9; B aggressive lymphoma protein; PARP-9; poly (ADP-ribose) polymerase 9; poly (ADP-ribose) polymerase family, member 9; Poly [ADP-ribose] polymerase 9; Protein mono-ADP-ribosyltransferase PARP9

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Gene Aliases: ARTD9; BAL; BAL1; MGC:7868; PARP9; RGD1307534

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UniProt ID: (Human) Q8IXQ6

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Entrez Gene ID: (Human) 83666, (Rat) 303905

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Function(s)

NAD+ ADP-ribosyltransferase activity protein binding

Process(es)

double-strand break repair cell migration regulation of response to interferon-gamma

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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PARP9 Polyclonal Antibody

PARP9 Antibody (17535-1-AP) in IHC (P)

Product Details

17535-1-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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