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Proteintech
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Immunogen sequence: YSTMSPLGS GAFGFVWTAV DKEKNKEVVV KFIKKEKVLE DCWIEDPKLG KVTLEIAILS RVEHANIIKV LDIFENQGFF QLVMEKHGSG LDLFAFIDRH PRLDEPLASY IFRQLVSAVG YLRLKDIIHR DIKDENIVIA EDFTIKLIDF GSAAYLERGK LFYTFCGTIE YCAPEVLMGN PYRGPELEMW SLGVTLYTLV FEENPFCELE ETVEAAIHPP YLVSKELMSL VSGLLQPVPE RRTTLEKLVT DPWVTQPVNL ADYTWEEVFR VNKPESGVLS AASLEMGNRS LSDVAQAQEL CGGPVPGEAP NGQGCLHPGD PRLLTS (999-1323 aa encoded by BC063585 )
PASK is an evolutionarily conserved protein present in yeast, flies, and mammals. PAS domains regulate the function of many intracellular signaling pathways in response to both extrinsic and intrinsic stimuli. It is a conserved gene product found in yeast as well as mammals. PASKIN contains two domains (PAS A and PAS B) as well as a serine/threonine kinase domain related to AMP kinases. PASKIN activity leads to decreased carbohydrate storage, as well as increased protein synthesis. PASKIN-dependent phosphorylation inhibits the activity of mammalian glycogen synthase.
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Protein Aliases: OTTMUSP00000024404; PAS domain-containing serine/threonine-protein kinase; PAS-kinase; paskin; per-arnt-sim (PAS) domain kinase
Gene Aliases: KIAA0135; mKIAA0135; PASK; PASKIN; STK37
UniProt ID: (Human) Q96RG2, (Mouse) Q8CEE6
Entrez Gene ID: (Human) 23178, (Mouse) 269224, (Rat) 301617
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