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Product Details
PA5-102606
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human PATE3(Accession B3GLJ2), corresponding to amino acid residues Y12-Q62.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2815924
Product Specific Information
Antibody detects endogenous levels of total PATE3.
Target Information
PATE3 (prostate and testis expressed protein 3), also known as PATE-DJ or HEL-127, is a 98 amino acid protein that contains one UPAR/Ly6 domain and belongs to the PATE family. PATE3 is a secreted protein that is expressed in prostate and testis. The gene that encodes PATE3 consists of around 3,490 bases and maps to human chromosome 11p15.5. Chromosome 11, which comprises approximately 4% of the human genome, is considered a gene and disease association-dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, while Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11-encoded genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Acrosomal vesicle protein HEL-127; Epididymis-specific ESC112; PATE-DJ; PATE-like protein DJ; prostate and testis expressed DJ; Prostate and testis expressed protein 3; secreted TFP/Ly-6/uPAR protein PATE-DJ
Gene Aliases: Gm17365; HEL-127; PATE-DJ; PATE3
UniProt ID: (Mouse) B3GLJ3, (Human) B3GLJ2
Entrez Gene ID: (Mouse) 100312956, (Human) 100169851, (Rat) 100361414
Performance Guarantee
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