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Immunogen sequence: DVEDYERRYL LSLEEERPAL MDDRKHKICS MYDNLRGKLP GQERPSDDHF VQIMCIRKGK RMVARILPFL STEQAADILM TTARNLPFLI KKDAQDEVLP CLLSPF; Positive Samples: Mouse kidney, Mouse brain, Rat liver; Cellular Location: Cytoplasm, Nucleus, Nucleus speckle, P-body, PML body
RNA-binding protein involved in deadenylation-dependent decapping of mRNAs, leading to the degradation of mRNAs. Acts as a scaffold protein that connects deadenylation and decapping machinery. Required for cytoplasmic mRNA processing body (P-body) assembly. In case of infection, required for translation and replication of hepatitis C virus (HCV).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: PAT1-like protein 1; Pat1b; Protein PAT1 homolog 1; Protein PAT1 homolog b
Gene Aliases: AV312086; Pat1b; Patl1; RGD1305514
UniProt ID: (Rat) B5DF93, (Mouse) Q3TD30
Entrez Gene ID: (Rat) 361736, (Mouse) 225929
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