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Invitrogen
PAX3 Recombinant Rabbit Monoclonal Antibody (9A6M6)
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FIGURE: 1 / 1
PAX3 Antibody (MA5-51354) in WB
Western blot analysis of PAX3 in various lysates. Samples were incubated with PAX3 Recombinant monoclonal antibody (Product # MA5-51354) using a dilution of 1:600 followed by HRP Goat Anti-Rabbit IgG (H+L) secondary antibody at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Product Details
MA5-51354
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
9A6M6
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 350-450 of human PAX3 (NP_852122.1).
Conjugate
Form
Liquid
Concentration
0.63 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_3093919
Product Specific Information
Immunogen sequence: SSSAYCLPST RHGFSSYTDS FVPPSGPSNP MNPTIGNGLS PQVMGLLTNH GGVPHQPQTD YALSPLTGGL EPTTTVSASC SQRLDHMKSL DSLPTSQSYC P
Target Information
Pax 3 (Paired Box 3) is a transcription factor that is involved in development of the peripheral nervous system, melanocytes, some vascular smooth muscle, and a number of other derivatives. It regulates neurogenesis in pre-migratory neural crest cells from the dorsal neural tube, and in myogenic progenitors in the presomitic mesoderm and the hypaxial somites. Alternative splicing results in isoforms having different C-termini.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: homeodomain protein PAX3; HuP2; MGC120381; MGC120382; MGC120383; MGC120384; MGC134778; paired box gene 3; paired box homeotic gene 3; Paired box protein Pax-3; paired domain gene 3; paired domain gene HuP2; PAX3/FKHR fusion
Gene Aliases: CDHS; HUP2; Pax-3; PAX3; Sp; splotch; WS1; WS3
UniProt ID: (Human) P23760, (Mouse) P24610
Entrez Gene ID: (Human) 5077, (Rat) 114502, (Mouse) 18505
negative regulation of transcription from RNA polymerase II promoter
neural crest cell migration
neural tube closure
transcription from RNA polymerase II promoter
heart development
muscle organ development
cell proliferation
positive regulation of cell proliferation
regulation of somitogenesis
cell migration
spinal cord association neuron differentiation
neural tube development
gliogenesis
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
developmental pigmentation
neuron fate commitment
skeletal muscle organ development
mammary gland specification
apoptotic process
nervous system development
sensory perception of sound
organ morphogenesis
neural crest formation
transcription, DNA-templated
regulation of transcription, DNA-templated
multicellular organism development
skeletal muscle cell differentiation
cardiac muscle cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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