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Invitrogen
PAX4 Polyclonal Antibody
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Product Details
PA5-19237
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide sequence (GKLATATSLPEDTVR) corresponding to the internal amino acids of PAX4 (aa 201-215).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_11001744
Product Specific Information
This antibody is predicted to react with canine and rat based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 64,000.
Target Information
This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The paired box 4 gene is involved in pancreatic islet development and mouse studies have demonstrated a role for this gene in differentiation of insulin-producing beta cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MGC129960; paired box gene 4; Paired box protein Pax-4; paired domain gene 4
Gene Aliases: KPD; MODY9; Pax-4; Pax4
UniProt ID: (Mouse) P32115
Entrez Gene ID: (Human) 5078, (Mouse) 18506
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
circadian rhythm
organ morphogenesis
cell differentiation
endocrine pancreas development
response to drug
negative regulation of apoptotic process
positive regulation of cell differentiation
response to cAMP
retina development in camera-type eye
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
multicellular organism development
regulation of cell differentiation
negative regulation of transcription, DNA-templated
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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