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PBX3 Polyclonal Antibody

PBX3 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 4

PBX3 Antibody (12571-1-AP) in ICC/IF

Immunofluorescent analysis of ( 4% PFA) fixed HeLa cells using 12571-1-AP (PBX3 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

PBX3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

PBX3 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

12571-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 7 publications 7 publications

Immunohistochemistry (IHC)

View 3 publications 3 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

1:50-1:500

View 3 publications 3 publications

Immunoprecipitation (IP)

0.5-4.0 µg

View 1 publication 1 publication

ChIP assay (ChIP)

View 1 publication 1 publication

RNA Immunoprecipitation (RIP)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

PBX3 Fusion Protein Ag3239 (19-367 aa encoded by BC016977)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.13 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: QLMRLDNML LAEGVSGPEK GGGSAAAAAA AAASGGSSDN SIEHSDYRAK LTQIRQIYHT ELEKYEQACN EFTTHVMNLL REQSRTRPIS PKEIERMVGI IHRKFSSIQM QLKQSTCEAV MILRSRFLDA RRKRRNFSKQ ATEILNEYFY SHLSNPYPSE EAKEELAKKC SITVSQSLVK DPKERGSKGS DIQPTSVVSN WFGNKRIRYK KNIGKFQEEA NLYAAKTAVT AAHAVAAAVQ NNQTNSPTTP NSGSSGSFNL PNSGDMFMNM QSLNGDSYQG SQVGANVQSQ VDTLRHVINQ TGGYSDGLGG NSLYSPHNLN ANGGWQDATT PSSVTSPTEG PGSVHSDTSN (19-367 aa encoded by BC016977)

Target Information

PBX3 is a transcriptional activator that binds the sequence 5'-ATCAATCAA-3'.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

USF1-ATRAP-PBX3 Axis Promote Breast Cancer Glycolysis and Malignant Phenotype by Activating AKT/mTOR Signaling.

International journal of biological sciences

Wang D,Jin X,Lei M,Jiang Y,Liu Y,Yu F,Guo Y,Han B,Yang Y,Sun W,Liu Y,Zeng G,Liu F,Hu J,Chen X

Thu Apr 14 00:00:00 UTC 2022

USF1-ATRAP-PBX3 Axis Promote Breast Cancer Glycolysis and Malignant Phenotype by Activating AKT/mTOR Signaling.

International journal of biological sciences

Wang D,Jin X,Lei M,Jiang Y,Liu Y,Yu F,Guo Y,Han B,Yang Y,Sun W,Liu Y,Zeng G,Liu F,Hu J,Chen X

Thu Apr 14 00:00:00 UTC 2022

USF1-ATRAP-PBX3 Axis Promote Breast Cancer Glycolysis and Malignant Phenotype by Activating AKT/mTOR Signaling.

International journal of biological sciences

Wang D,Jin X,Lei M,Jiang Y,Liu Y,Yu F,Guo Y,Han B,Yang Y,Sun W,Liu Y,Zeng G,Liu F,Hu J,Chen X

Thu Apr 14 00:00:00 UTC 2022

USF1-ATRAP-PBX3 Axis Promote Breast Cancer Glycolysis and Malignant Phenotype by Activating AKT/mTOR Signaling.

International journal of biological sciences

Wang D,Jin X,Lei M,Jiang Y,Liu Y,Yu F,Guo Y,Han B,Yang Y,Sun W,Liu Y,Zeng G,Liu F,Hu J,Chen X

Thu Apr 14 00:00:00 UTC 2022

scRNA-Seq Reveals New Enteric Nervous System Roles for GDNF, NRTN, and TBX3.

Cellular and molecular gastroenterology and hepatology

Wright CM,Schneider S,Smith-Edwards KM,Mafra F,Leembruggen AJL,Gonzalez MV,Kothakapa DR,Anderson JB,Maguire BA,Gao T,Missall TA,Howard MJ,Bornstein JC,Davis BM,Heuckeroth RO

Tue Mar 08 00:00:00 UTC 2022

LncRNA H19 suppresses pyroptosis of cardiomyocytes to attenuate myocardial infarction in a PBX3/CYP1B1-dependent manner.

Molecular and cellular biochemistry

Han Y,Dong B,Chen M,Yao C

Mon Mar 01 00:00:00 UTC 2021

P2X7 promotes the progression of MLL-AF9 induced acute myeloid leukemia by upregulation of Pbx3.

Haematologica

Feng W,Yang X,Wang L,Wang R,Yang F,Wang H,Liu X,Ren Q,Zhang Y,Zhu X,Zheng G

Sat May 01 00:00:00 UTC 2021

Circular RNA circCORO1C promotes laryngeal squamous cell carcinoma progression by modulating the let-7c-5p/PBX3 axis.

Molecular cancer

Wu Y,Zhang Y,Zheng X,Dai F,Lu Y,Dai L,Niu M,Guo H,Li W,Xue X,Bo Y,Guo Y,Qin J,Qin Y,Liu H,Zhang Y,Yang T,Li L,Zhang L,Hou R,Wen S,An C,Li H,Xu W,Gao W

Tue Jun 02 00:00:00 UTC 2020

Long non-coding RNA HNF1A-AS1 upregulates OTX1 to enhance angiogenesis in colon cancer via the binding of transcription factor PBX3.

Experimental cell research

Wu J,Meng X,Jia Y,Chai J,Wang J,Xue X,Dang T

Sat Aug 15 00:00:00 UTC 2020

Long non-coding RNA HNF1A-AS1 upregulates OTX1 to enhance angiogenesis in colon cancer via the binding of transcription factor PBX3.

Experimental cell research

Wu J,Meng X,Jia Y,Chai J,Wang J,Xue X,Dang T

Sat Aug 15 00:00:00 UTC 2020

PBX3 Promotes Tumor Growth and Angiogenesis via Activation of AT1R/VEGFR2 Pathway in Papillary Thyroid Carcinoma.

BioMed research international

Chen Q,Yu WY,Zhang HH,Zhang SZ,Fang J,Wu F,Ying HZ,Yu CH

Mon Nov 02 00:00:00 UTC 2020

An integrated approach to identify critical transcription factors in the protection against hydrogen peroxide-induced oxidative stress by Danhong injection.

Free radical biology & medicine

Zhang J,Guo F,Wei J,Xian M,Tang S,Zhao Y,Liu M,Song L,Geng Y,Yang H,Ding C,Huang L

Wed Nov 01 00:00:00 UTC 2017

An integrated approach to identify critical transcription factors in the protection against hydrogen peroxide-induced oxidative stress by Danhong injection.

Free radical biology & medicine

Zhang J,Guo F,Wei J,Xian M,Tang S,Zhao Y,Liu M,Song L,Geng Y,Yang H,Ding C,Huang L

Wed Nov 01 00:00:00 UTC 2017

MicroRNA-144-3p suppresses gastric cancer progression by inhibiting epithelial-to-mesenchymal transition through targeting PBX3.

Biochemical and biophysical research communications

Li B,Zhang S,Shen H,Li C

Sat Mar 04 00:00:00 UTC 2017

MicroRNA-144-3p suppresses gastric cancer progression by inhibiting epithelial-to-mesenchymal transition through targeting PBX3.

Biochemical and biophysical research communications

Li B,Zhang S,Shen H,Li C

Sat Mar 04 00:00:00 UTC 2017

Screening and identification of critical transcription factors involved in the protection of cardiomyocytes against hydrogen peroxide-induced damage by Yixin-shu.

Scientific reports

Zhang J,Geng Y,Guo F,Zhang F,Liu M,Song L,Ma Y,Li D,Zhang Y,Xu H,Yang H

Tue Oct 24 00:00:00 UTC 2017

Screening and identification of critical transcription factors involved in the protection of cardiomyocytes against hydrogen peroxide-induced damage by Yixin-shu.

Scientific reports

Zhang J,Geng Y,Guo F,Zhang F,Liu M,Song L,Ma Y,Li D,Zhang Y,Xu H,Yang H

Tue Oct 24 00:00:00 UTC 2017

Screening and identification of critical transcription factors involved in the protection of cardiomyocytes against hydrogen peroxide-induced damage by Yixin-shu.

Scientific reports

Zhang J,Geng Y,Guo F,Zhang F,Liu M,Song L,Ma Y,Li D,Zhang Y,Xu H,Yang H

Tue Oct 24 00:00:00 UTC 2017

miR-320a regulates cell proliferation and apoptosis in multiple myeloma by targeting pre-B-cell leukemia transcription factor 3.

Biochemical and biophysical research communications

Lu Y,Wu D,Wang J,Li Y,Chai X,Kang Q

Fri May 13 00:00:00 UTC 2016

miR-320a regulates cell proliferation and apoptosis in multiple myeloma by targeting pre-B-cell leukemia transcription factor 3.

Biochemical and biophysical research communications

Lu Y,Wu D,Wang J,Li Y,Chai X,Kang Q

Fri May 13 00:00:00 UTC 2016

miR-320a regulates cell proliferation and apoptosis in multiple myeloma by targeting pre-B-cell leukemia transcription factor 3.

Biochemical and biophysical research communications

Lu Y,Wu D,Wang J,Li Y,Chai X,Kang Q

Fri May 13 00:00:00 UTC 2016

miR-320a regulates cell proliferation and apoptosis in multiple myeloma by targeting pre-B-cell leukemia transcription factor 3.

Biochemical and biophysical research communications

Lu Y,Wu D,Wang J,Li Y,Chai X,Kang Q

Fri May 13 00:00:00 UTC 2016

PBX3 promotes gastric cancer invasion and metastasis by inducing epithelial-mesenchymal transition.

Oncology letters

Wang S,Li C,Wang W,Xing C

Tue Nov 01 00:00:00 UTC 2016

PBX3 promotes gastric cancer invasion and metastasis by inducing epithelial-mesenchymal transition.

Oncology letters

Wang S,Li C,Wang W,Xing C

Tue Nov 01 00:00:00 UTC 2016

PBX3 is overexpressed in gastric cancer and regulates cell proliferation.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Li Y,Sun Z,Zhu Z,Zhang J,Sun X,Xu H

Thu May 01 00:00:00 UTC 2014

Bioinformatics

Protein Aliases: Homeobox protein PBX3; pre-B-cell leukemia homeobox 3; Pre-B-cell leukemia transcription factor 3

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Gene Aliases: PBX3

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UniProt ID: (Human) P40426, (Mouse) O35317

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Entrez Gene ID: (Human) 5090, (Rat) 311876, (Mouse) 18516

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Function(s)

RNA polymerase II distal enhancer sequence-specific DNA binding transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding transcription factor activity, sequence-specific DNA binding sequence-specific DNA binding DNA binding protein binding

Process(es)

regulation of respiratory gaseous exchange by neurological system process regulation of transcription, DNA-templated transcription from RNA polymerase II promoter respiratory gaseous exchange adult locomotory behavior dorsal spinal cord development positive regulation of transcription from RNA polymerase II promoter neuron development anterior compartment pattern formation posterior compartment specification transcription, DNA-templated

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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PBX3 Polyclonal Antibody

PBX3 Antibody (12571-1-AP) in ICC/IF

Product Details

12571-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

ChIP assay (ChIP)

RNA Immunoprecipitation (RIP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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