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Product Details
13645-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PCDH1 Fusion Protein Ag4591 (61-381 aa encoded by BC035812)
Conjugate
Form
Liquid
Concentration
0.19 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: VYKVPEEQP PNTLIGSLAA DYGFPDVGHL YKLEVGAPYL RVDGKTGDIF TTETSIDREG LRECQNQLPG DPCILEFEVS ITDLVQNGSP RLLEGQIEVQ DINDNTPNFA SPVITLAIPE NTNIGSLFPI PLASDRDAGP NGVASYELQA GPEAQELFGL QVAEDQEEKQ PQLIVMGNLD RERWDSYDLT IKVQDGGSPP RASSALLRVT VLDTNDNAPK FERPSYEAEL SENSPIGHSV IQVKANDSDQ GANAEIEYTF HQAPEVVRRL LRLDRNTGLI TVQGPVDRED LSTLRFSVLA KDRGTNPKSA RAQVVVTVKD MN (61-381 aa encoded by BC035812)
Target Information
Protocadherin 1, also known as PCDH1 and cadherin-like protein 1, is a transmembrane protein involved in cell-cell adhesion. Protocadherin 1 belongs to a group of cadherin-like proteins termed delta1-protocadherins, which consists of protocadherin-1, -7, -9, and -11(X/Y). The delta1-protocadherins have seven extracellular cadherin-repeats, a transmembrane domain, and a cytoplasmic domain, and can be expressed in two isoforms, short or long. Expression of protocadherin 1 is regulated both temporally and spatially, and plays a role both in early development and mature tissues. In mice, it is expressed in a number of tissues and organs, including the brain, spinal cord, peripheral ganglia, inner ear, hair follicles, kidney, reproductive organs, prostate, and the seminal gland. Notably, protocadherin 1 is a susceptibility gene for Bronchial Hyperresponsiveness in humans. Expression of protocadherin 1 has also been identified on human pluripotent stem cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: cadherin-like 1; Cadherin-like protein 1; PC42; protocadherin 1 (cadherin-like 1); protocadherin 42; Protocadherin-1; Protocadherin-42
Gene Aliases: 2010005A06Rik; AI585920; PC42; PCDH1; PCDH42
UniProt ID: (Human) Q08174
Entrez Gene ID: (Human) 5097, (Mouse) 75599, (Rat) 307481
Performance Guarantee
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