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Product Details
PA5-53686
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human PCDH18. Recombinant protein control fragment (Product #RP-90578).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2645252
Product Specific Information
Immunogen sequence: IHKGDITLVP TINGTLPIRS HHRSSPSSSP TLERGQMGSR QSHNSHQSLN SLVTISSNHV PENFSLELTH ATPAVEQVSQ LLSMLHQGQY QPRPSFRGNK YSRSYR
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 99%.
Target Information
Protocadherins comprise the largest group within the cadherin family of calcium-dependent cell-cell adhesion molecules. Protocadherin 18 (PCDH18) was initially identified through screening of human and mouse ESTs using conserved cytoplasmic domain motifs. Tissue screening revealed PCDH18 broad expression in tissues such as brain, liver, heart, kidney, lung, and trachea. PCDH18 expression is also temporally and spatially regulated in the mouse embryonic brain and interacts with Disabled-1, an intracellular adapter protein involved in neuronal migration and cell positioning during mammalian brain development. PCDH18 was also found to be expressed in the developing zebrafish neural tube and central nervous system, lending support to the hypothesis that PCDH18 may play a role during brain development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZP434B0923; Protocadherin 18; protocadherin 68-like protein; Protocadherin-18
Gene Aliases: 3110038E07Rik; BB095589; KIAA1562; PCDH18; PCDH68L
UniProt ID: (Human) Q9HCL0, (Mouse) Q8VHR0
Entrez Gene ID: (Human) 54510, (Mouse) 73173
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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