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Abnova
PCM1 Polyclonal Antibody, MaxPab™
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Product Details
H00005108-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PCM1 (AAH00453.1, 1 a.a. approximately 530 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MATGGGPFED GMNDQDLPNW SNENVDDRLN NMDWGAQQKK ANRSSEKNKK KFGVESDKRV TNDISPESSP GVGRRRTKTP HTFPHSRYMS QMSVPEQAEL EKLKQRINFS DLDQRSIGSD SQGRATAANN KRQLSENRKP FNFLPMQINT NKSKDASTSP PNRETIGSAQ CKELFASALS NDLLQNCQVS EEDGRGEPAM ESSQIVSRLV QIRDYITKAS SMREDLVEKN ERSANVERLT HLIDHLKEQE KSYMKFLKKI LARENEEEDV RTIDSAVGSG SVAESTSLNI DVQSEASDTT ARDPQQEPME EIENLKKQHD LLKRMLQQQE QLRALQGRQA ALLALQHKAE QAIAVMDDSV VAETAGSLSG VSITSELNEE LNDLIQRFHN QLRDSQPPAV PDNRRQAESL SLTREVSQSR KPSASERLPD EKVELFSKMR VLQEKKQKMD KLLGELHTLR DQHLNNSSSS PQRSVDQRST SAPSASVGLA PVVNGESNSL TSSVPYPTAS LVSQNESENE GHLNPSEKLQ
Target Information
PCM-1 is required for centrosome assembly and function. This protein is essential for the correct localization of several centrosomal proteins including CEP250, CETN3, PCNT and NEK2. The protein is required to anchor microtubules to the centrosome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: hPCM-1; PCM-1; Pericentriolar material 1 protein; pericentriolar material 1, PCM1
Gene Aliases: PCM1; PTC4; RET/PCM-1
UniProt ID: (Human) Q15154
Entrez Gene ID: (Human) 5108
G2/M transition of mitotic cell cycle
neuron migration
interkinetic nuclear migration
cytoplasmic microtubule organization
microtubule anchoring
microtubule anchoring at centrosome
nonmotile primary cilium assembly
intraciliary transport involved in cilium morphogenesis
cilium assembly
negative regulation of neurogenesis
centrosome organization
protein localization to centrosome
positive regulation of intracellular protein transport
neuronal stem cell population maintenance
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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