Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
BS-11924R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human PCPTP1, amino acids 165-270.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domains, and thus represents a receptor-type PTP. The similar gene predominately expressed in mouse brain was found to associate with, and thus regulate the activity and cellular localization of MAP kinases. The rat counterpart of this gene was reported to be regulated by the nerve growth factor, which suggested the function of this gene in neuronal growth and differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: Ch-1 PTPase; Ch-1PTPase; ECPPT; NC-PTPCOM1; PC12-PTP1; Phosphotyrosine phosphatase 13; protein tyrosine phosphatase Cr1PTPase; protein tyrosine phosphatase PCPTP1; protein tyrosine phosphatase, receptor type, R; protein-tyrosine phosphatase NC-PTPCOM1; Protein-tyrosine phosphatase PCPTP1; Protein-tyrosine-phosphatase SL; protein-tyrosine-phosphatase-SL; R-PTP-R; Receptor-type tyrosine-protein phosphatase R; STEP-like PTPase; Tyrosine phosphatase CBPTP
Gene Aliases: EC-PTP; ECPTP; Gmcp1; mPTP213; PCPTP1; Ptp; PTP-SL; Ptp13; PTPBR7; PTPRQ; PTPRR; RPTPRR
UniProt ID: (Human) Q15256, (Mouse) Q62132, (Rat) O08617
Entrez Gene ID: (Human) 5801, (Mouse) 19279, (Rat) 94202
protein dephosphorylation
negative regulation of epithelial cell migration
dephosphorylation
peptidyl-tyrosine dephosphorylation
ERBB2 signaling pathway
negative regulation of ERK1 and ERK2 cascade
in utero embryonic development
nervous system development
neuron differentiation
regulation of homophilic cell adhesion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support