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Invitrogen
PCSK6 Polyclonal Antibody
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Product Details
PA5-32966
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Horse,
Human,
Non-human primate,
Rabbit,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 14 amino acid peptide from Cys-rich motif (CRM) region of human PACE4.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2550427
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Rat, Bovine, Elephant, Horse, Rabbit (100%); Gibbon, Mouse, Dog, Panda, Pig (93%); Turkey, Chicken (86%).
Immunohistochemistry with formalin-fixed paraffin-embedded tissues requires pretreatment with Proteinase K.
Target Information
The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease that can cleave precursor protein at their paired basic amino acid processing sites. Some of its substrates are - transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: kexin-like protease PC7A; Paired basic amino acid cleaving enzyme 4; paired basic amino acid cleaving system 4; Proprotein convertase subtilisin/kexin type 6; SPC4; Subtilisin - like endoprotease; Subtilisin-like proprotein convertase 4; Subtilisin/kexin-like protease PACE4
Gene Aliases: PACE4; PCSK6; SPC4
UniProt ID: (Human) P29122, (Rat) Q63415
Entrez Gene ID: (Human) 5046, (Rabbit) 100347173, (Rat) 25507
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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