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PDCD7 Antibody (PA5-88369) in WB
Western blot analysis of PDCD7 in extracts of various cell lines. Samples were incubated with PDCD7 Polyclonal antibody (Product # PA5-88369) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
Product Details
PA5-88369
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 396-485 of human PDCD7 (NP_0056981)
Conjugate
Form
Liquid
Concentration
0.64 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2804864
Product Specific Information
Immunogen sequence: EKEKILLQKR EIESKLFGDP DEFPLAHLLE PFRQYYLQAE HSLPALIQIR HDWDQYLVPS DHPKGNFVPQ GWVLPPLPSN DIWATAVKLH; Positive Samples: HT-29, HeLa, Jurkat, MCF-7, Rat thymus; Cellular Location: Nucleus
Target Information
PDCD7 is a protein with sequence similarity to a mouse protein originally identified in embryonic stem cells. In mouse T-cell lines, this protein appears to be related to glucocorticoid- and staurine-induced apoptotic pathways, and to be linked to ceramide-mediated signaling. These observations suggest that this gene product is involved in specific apoptotic processes in T-cells. This gene encodes a protein with sequence similarity to a mouse protein originally identified in embryonic stem cells. In mouse T-cell lines, this protein appears to be related to glucocorticoid- and staurine-induced apoptotic pathways, and to be linked to ceramide-mediated signaling. These observations suggest that this gene product is involved in specific apoptotic processes in T-cells.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: apoptosis-related protein ES18; ES18; H MGC22015; hES18; MGC22015; Programmed cell death protein 7; U11/U12 snRNP 59K
Gene Aliases: ES18; HES18; PDCD7
UniProt ID: (Human) Q8N8D1
Entrez Gene ID: (Human) 10081, (Rat) 363082
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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