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Invitrogen
PDDC1 Polyclonal Antibody
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Product Details
PA5-52613
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human PDDC1. Recombinant protein control fragment (Product #RP-89869).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2645321
Product Specific Information
Immunogen sequence: KPICAVGHGV AALCCATNED RSWVFDSYSL TGPSVCELVR APGFARLPLV VEDFVKDSGA CFSASEPDAV HVVLDRHLVT GQNASSTVPA VQNLLFLCGS RK
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 90%.
Target Information
The PDDC1 (Parkinson Disease 7 Domain Containing 1) gene encodes a protein that is part of the DJ-1 protein family, known for its role in protecting cells against oxidative stress and neurodegenerative conditions. PDDC1 has been implicated in various cellular processes such as transcription regulation, response to oxidative damage, and cellular homeostasis. It is located on human chromosome 12 and is expressed in several tissues, including the brain. Although its exact function remains to be fully elucidated, PDDC1 shares homology with Parkinson's disease-associated protein DJ-1, suggesting a potential role in neuroprotection. Research indicates that PDDC1 might be involved in neural development and survival, and its dysregulation could contribute to diseases involving oxidative stress and neurodegeneration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ferry endosomal RAB5 effector complex subunit 5; Fy-5; Glutamine amidotransferase-like class 1 domain-containing protein 1; Parkinson disease 7 domain-containing protein 1
Gene Aliases: FERRY5; GATD1; PDDC1
UniProt ID: (Human) Q8NB37
Entrez Gene ID: (Human) 347862
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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