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Fabgennix
PDE1C Polyclonal Antibody, Biotin
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Product Details
PD1C-C-BIOTIN
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to unique amino acid sequence on PDE1C gene.
Conjugate
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1C, are calmodulin -dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al., 1992 ).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C; Cam-PDE 1C; cyclic nucleotide phosphodiesterase 1 C; Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C; Hcam3; Human 3',5' cyclic nucleotide phosphodiesterase (HSPDE1C1A); phosphodiesterase 1C calmodulin-dependent (70kD); phosphodiesterase 1C, calmodulin-dependent 70kDa
Gene Aliases: cam-PDE 1C; hCam-3; Hcam3; PDE1C; Pde1c2
UniProt ID: (Human) Q14123, (Mouse) Q64338, (Rat) Q63421
Entrez Gene ID: (Human) 5137, (Mouse) 18575, (Rat) 81742
calmodulin-dependent cyclic-nucleotide phosphodiesterase activity
calmodulin binding
metal ion binding
3',5'-cyclic-nucleotide phosphodiesterase activity
3',5'-cyclic-AMP phosphodiesterase activity
phosphoric diester hydrolase activity
hydrolase activity
cAMP binding
calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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