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Product Details
PD4B3-221AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide selective only for PDE4B3 subtype.
Conjugate
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Target Information
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 3',5'-cyclic AMP phosphodiesterase; 3',5'-cyclic-AMP phosphodiesterase 4B; cAMP-specific 3',5'-cyclic phosphodiesterase 4B; cAMP-specific phosphodiesterase 4B; DPDE4; dunce-like phosphodiesterase E4; PDE32; Pde4b; Phosphodiesterase 4B cAMP-specific (dunce; Phosphodiesterase 4B, cAMP-specific (dunce; phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila)
Gene Aliases: DPDE4; dunce; PDE4/IVb; PDE4B; Pde4B1; Pde4B2; Pde4B3; Pde4B4; PDEIVB; R74983
UniProt ID: (Human) Q07343, (Rat) P14646
Entrez Gene ID: (Human) 5142, (Rat) 24626, (Mouse) 18578
neutrophil homeostasis
cAMP catabolic process
smooth muscle contraction
signal transduction
metabolic process
neutrophil chemotaxis
positive regulation of interferon-gamma production
positive regulation of interleukin-2 production
cellular response to drug
T cell receptor signaling pathway
leukocyte migration
cellular response to lipopolysaccharide
cellular response to epinephrine stimulus
regulation of cardiac muscle cell contraction
regulation of high voltage-gated calcium channel activity
negative regulation of relaxation of cardiac muscle
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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