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Invitrogen
PDE6D Recombinant Rabbit Monoclonal Antibody (HL1359)
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FIGURE: 1 / 8
PDE6D Antibody (MA5-47012) in IHC (P)
Immunohistochemistry analysis of PDE6D in paraffin-embedded mouse eye. Green: PDE6D stained by PDE6D monoclonal antibody (Product # MA5-47012) diluted at 1:100. Red: beta Tubulin 3/ Tuj1, a neural marker, stained by beta Tubulin 3/ Tuj1 antibody [GT11710] diluted at 1:500. Blue: Fluoroshield with DAPI. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min.
Product Details
MA5-47012
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Dog,
Cat,
Human,
Mouse,
Rat,
Zebrafish
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
HL1359
Immunogen
Full length human PDE6D Recombinant protein
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2938084
Product Specific Information
Store as concentrated solution.
Centrifuge briefly prior to opening vial.
Target Information
PrBP/delta, previously known as PDE6/delta, is the effector enzyme in the G protein-mediated signal transduction cascade in the visual system. There are five different subunits consisting of rod and cone specific catalytic subunits: alpha (Cone), alpha (Rod), and beta (Rod), the inhibitory subunit gamma, and subunit delta of unknown function (which likely interacts with many other proteins besides the PDE6 family). PRBP/delta has been implicated in the transport and membrane targeting of prenylated proteins (including PDE6) from their site of synthesis in the inner segment to their final destination in the outer segment of rods and cones (Norton et. al., 2005).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cGMP-phosphodiesterase delta subunit; GMP-PDE delta; pde6D gene for cGMP-phosphodiesterase delta subunit; phosphodiesterase 6D, cGMP-specific, rod, delta; Protein p17; Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta
Gene Aliases: AI841218; JBTS22; PDE6D; PDED; PrBP/delta; zgc:92605
UniProt ID: (Dog) Q9XT54, (Human) O43924, (Mouse) O55057
Entrez Gene ID: (Dog) 403781, (Human) 5147, (Rat) 363272, (Mouse) 18582, (Zebrafish) 436981
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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