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Proteintech
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Immunogen sequence: MSCLMVERC GEILFENPDQ NAKCVCMLGD IRLRGQTGVR AERRGSYPFI DFRLLNSTTY SGEIGTKKKV KRLLSFQRYF HASRLLRGII PQAPLHLLDE DYLGQARHML SKVGMWDFDI FLFDRLTNGN SLVTLLCHLF NTHGLIHHFK LDMVTLHRFL VMVQEDYHSQ NPYHNAVHAA DVTQAMHCYL KEPKLASFLT PLDIMLGLLA AAAHDVDHPG VNQPFLIKTN HHLANLYQNM SVLENHHWRS TIGMLRESRL LAHLPKEMTQ DIEQQLGSLI LATDINRQNE FLTRLKAHLH NKDLRLEDAQ DRHFMLQIAL KCADICNPCR IWEMSKQWSE RVCEEFYRQG ELEQKFELEI SPLCNQQKDS IPSIQIGFMS YIVEPLFREW AHFTGNSTLS ENMLGHLAHN KAQWKSLLPR QHRSRGSSGS GPDHDHAGQG TESEEQEGDS P (1-450 aa encoded by BC075082)
The 3', 5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3', 5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a cAMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 3',5'-cyclic-AMP phosphodiesterase 7B; cAMP-specific 3',5'-cyclic phosphodiesterase 7B; cAMP-specific phosphodiesterase 7B; high-affinity cAMP-specific 3',5'-cyclic phosphodiesterase; MGC88256; rolipram-insensitive phosphodiesterase type 7; RP11-472E5.2
Gene Aliases: bA472E5.1; PDE7B
UniProt ID: (Human) Q9NP56, (Mouse) Q9QXQ1
Entrez Gene ID: (Human) 27115, (Rat) 140929, (Mouse) 29863
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