Bioss

PDGF A Polyclonal Antibody, Alexa Fluor™ 594

View all (26) PDGF-A antibodies

Promotion

View available promotion(s)

Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

BS-10073R-A594

Applications
Tested Dilution
Publications

Western Blot (WB)

1:300-5,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200
-

Immunohistochemistry (Frozen) (IHC (F))

1:50-1:200
-

Immunocytochemistry (ICC/IF)

1:50-1:200
-

Flow Cytometry (Flow)

1:20-1:100
-
Product Specifications

Species Reactivity

Human, Mouse, Rabbit

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from rabbit PDGF-A (102-213).
View immunogen

Conjugate

Alexa Fluor™ 594 Alexa Fluor™ 594 Alexa Fluor™ 594

Excitation/Emission Max

590/618 nm View spectra spectra

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

TBS, pH 7.4, with 1% BSA, 50% glycerol

Contains

0.03% ProClin 300

Storage conditions

-20°C or -80°C if preferred

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

This gene encodes a member of the protein family comprised of both platelet-derived growth factors (PDGF) and vascular endothelial growth factors (VEGF). The encoded preproprotein is proteolytically processed to generate platelet-derived growth factor subunit A, which can homodimerize, or alternatively, heterodimerize with the related platelet-derived growth factor subunit B. These proteins bind and activate PDGF receptor tyrosine kinases, which play a role in a wide range of developmental processes. Alternative splicing results in multiple transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?
Let us know so we can reference it here.
Cite this product

Bioinformatics

Protein Aliases: PDGF A-chain; PDGF subunit A; PDGF-1; Platelet-derived growth factor A chain; platelet-derived growth factor A-chain; platelet-derived growth factor alpha chain; Platelet-derived growth factor alpha polypeptide; Platelet-derived growth factor subunit A; Platelet-derived growth factor subunit A-like

View more View less

Gene Aliases: PDGF-A; PDGF1; PDGFA

View more View less

UniProt ID: (Human) P04085, (Mouse) P20033

View more View less

Entrez Gene ID: (Rabbit) 100352388, (Human) 5154, (Mouse) 18590

View more View less

Function(s)
Ras guanyl-nucleotide exchange factor activity platelet-derived growth factor receptor binding protein binding collagen binding growth factor activity protein homodimerization activity phosphatidylinositol-4,5-bisphosphate 3-kinase activity protein heterodimerization activity platelet-derived growth factor binding
Process(es)
angiogenesis hair follicle development positive regulation of mesenchymal cell proliferation multicellular organism development positive regulation of cell proliferation response to wounding organ morphogenesis negative regulation of phosphatidylinositol biosynthetic process negative regulation of platelet activation positive regulation of phosphatidylinositol 3-kinase signaling regulation of smooth muscle cell migration cell projection assembly actin cytoskeleton organization positive regulation of cell migration positive regulation of protein autophosphorylation positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway positive regulation of MAP kinase activity positive regulation of MAPK cascade skin development positive regulation of DNA replication platelet-derived growth factor receptor signaling pathway positive regulation of fibroblast proliferation lung alveolus development digestive tract development regulation of peptidyl-tyrosine phosphorylation negative chemotaxis positive regulation of cell division positive regulation of protein kinase B signaling bone development regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling positive regulation of ERK1 and ERK2 cascade embryonic lung development MAPK cascade response to hypoxia cell activation platelet degranulation transforming growth factor beta receptor signaling pathway cell-cell signaling response to inorganic substance regulation of phosphatidylinositol 3-kinase signaling extracellular matrix organization response to estradiol response to retinoic acid regulation of actin cytoskeleton organization wound healing response to drug positive regulation of GTPase activity phosphatidylinositol phosphorylation phosphatidylinositol-mediated signaling inner ear development regulation of glomerular mesangial cell proliferation regulation of DNA biosynthetic process
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support