PDGF-A/B Monoclonal Antibody (1G10)

Ras guanyl-nucleotide exchange factor activity platelet-derived growth factor receptor binding protein binding collagen binding growth factor activity protein homodimerization activity phosphatidylinositol-4,5-bisphosphate 3-kinase activity protein heterodimerization activity platelet-derived growth factor binding superoxide-generating NADPH oxidase activator activity chemoattractant activity identical protein binding receptor binding

angiogenesis response to hypoxia hair follicle development positive regulation of mesenchymal cell proliferation transforming growth factor beta receptor signaling pathway blood coagulation positive regulation of cell proliferation response to wounding organ morphogenesis response to organic substance response to inorganic substance negative regulation of phosphatidylinositol biosynthetic process negative regulation of platelet activation positive regulation of phosphatidylinositol 3-kinase signaling regulation of smooth muscle cell migration cell projection assembly actin cytoskeleton organization positive regulation of cell migration positive regulation of protein autophosphorylation response to estradiol response to retinoic acid positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway wound healing response to drug positive regulation of MAP kinase activity positive regulation of MAPK cascade skin development positive regulation of DNA replication platelet-derived growth factor receptor signaling pathway positive regulation of fibroblast proliferation lung alveolus development digestive tract development inner ear development regulation of peptidyl-tyrosine phosphorylation negative chemotaxis positive regulation of cell division positive regulation of protein kinase B signaling regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling positive regulation of ERK1 and ERK2 cascade regulation of glomerular mesangial cell proliferation embryonic lung development regulation of DNA biosynthetic process multicellular organism development bone development embryonic placenta development positive regulation of endothelial cell proliferation monocyte chemotaxis positive regulation of glomerular filtration protein phosphorylation substrate-dependent cell migration synapse assembly heart development positive regulation of smooth muscle cell migration neuron remodeling peptidyl-serine phosphorylation peptidyl-tyrosine phosphorylation glial cell development negative regulation of cell migration negative regulation of protein binding activation of protein kinase activity activation of protein kinase B activity paracrine signaling positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway eye photoreceptor cell development positive regulation of blood vessel endothelial cell migration positive regulation of phosphatidylinositol 3-kinase activity positive regulation of cyclin-dependent protein serine/threonine kinase activity positive regulation of fibroblast growth factor receptor signaling pathway positive regulation of mitotic nuclear division negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of vasoconstriction negative regulation of vasodilation positive regulation of mitotic cell cycle, embryonic blood vessel morphogenesis positive regulation of smooth muscle cell proliferation positive regulation of peptidyl-tyrosine phosphorylation positive chemotaxis positive regulation of chemotaxis retina development in camera-type eye cell chemotaxis branching involved in salivary gland morphogenesis epithelial cell proliferation involved in salivary gland morphogenesis cardiac vascular smooth muscle cell differentiation positive regulation of protein tyrosine kinase activity retina vasculature development in camera-type eye cellular response to growth factor stimulus cellular response to mycophenolic acid positive regulation of glomerular mesangial cell proliferation metanephric glomerular mesangial cell development metanephric glomerular mesangial cell proliferation involved in metanephros development reactive oxygen species metabolic process positive regulation of calcium ion import positive regulation of hyaluronan biosynthetic process positive regulation of reactive oxygen species metabolic process positive regulation of DNA biosynthetic process positive regulation of metanephric mesenchymal cell migration DNA replication response to organic cyclic compound cell growth hemopoiesis response to insulin regulation of cell proliferation response to estrogen metanephric glomerular endothelium development MAPK cascade cell activation platelet degranulation cell-cell signaling regulation of phosphatidylinositol 3-kinase signaling extracellular matrix organization regulation of actin cytoskeleton organization positive regulation of GTPase activity phosphatidylinositol phosphorylation phosphatidylinositol-mediated signaling positive regulation of gene expression negative regulation of gene expression protein kinase C signaling negative regulation of pri-miRNA transcription from RNA polymerase II promoter positive regulation of pri-miRNA transcription from RNA polymerase II promoter positive regulation of vascular smooth muscle cell proliferation positive regulation of vascular associated smooth muscle cell migration negative regulation of vascular smooth muscle cell differentiation positive regulation of vascular smooth muscle cell dedifferentiation