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Proteintech
PDGFRL Polyclonal Antibody
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Product Details
16217-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PDGFRL Fusion Protein Ag9218 (1-375 aa encoded by BC010927)
Conjugate
Form
Liquid
Concentration
0.45 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MKVWLLLGL LLVHEALEDV TGQHLPKNKR PKEPGENRIK PTNKKVKPKI PKMKDRDSAN SAPKTQSIMM QVLDKGRFQK PAATLSLLAG QTVELRCKGS RIGWSYPAYL DTFKDSRLSV KQNERYGQLT LVNSTSADTG EFSCWVQLCS GYICRKDEAK TGSTYIFFTE KGELFVPSPS YFDVVYLNPD RQAVVPCRVT VLSAKVTLHR EFPAKEIPAN GTDIVYDMKR GFVYLQPHSE HQGVVYCRAE AGGRSQISVK YQLLYVAVPS GPPSTTILAS SNKVKSGDDI SVLCTVLGEP DVEVEFTWIF PGQKDERPVT IQDTWRLIHR GLGHTTRISQ SVITVEDFET IDAGYYICTA QNLQGQTTVA TTVEFS (1-375 aa encoded by B C010927)
Target Information
PDGFRL bears significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in the PDGFRL gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests PDGFRL may function as a tumor suppressor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: PDGF receptor beta-like tumor suppressor; PDGFR-like protein; Platelet-derived growth factor receptor-like protein; platelet-derived growth factor-beta-like tumor suppressor
Gene Aliases: 1110039P19Rik; AV013190; PDGFRL; PDGRL; PRLTS
UniProt ID: (Human) Q15198, (Mouse) Q6PE55, (Rat) Q5RJP7
Entrez Gene ID: (Human) 5157, (Mouse) 68797, (Rat) 290771
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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