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Abnova
PDK3 Monoclonal Antibody (3A1)
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Product Details
H00005165-M02
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
3A1
Immunogen
PDK3 (AAH15948, 174 a.a. approximately 263 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: GDTNPVHPKH IGSIDPTCNV ADVVKDAYET AKMLCEQYYL VAPELEVEEF NAKAPDKPIQ VVYVPSHLFH MLFELFKNSM RATVELYEDR
Target Information
PDK3 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial; pyruvate dehydrogenase; Pyruvate dehydrogenase kinase isoform 3; pyruvate dehydrogenase kinase, isoenzyme 3; pyruvate dehydrogenase, lipoamide, kinase isozyme 3, mitochondrial
Gene Aliases: CMTX6; GS1-358P8.4; PDHK3; PDK3
UniProt ID: (Human) Q15120
Entrez Gene ID: (Human) 5165
glucose metabolic process
regulation of acetyl-CoA biosynthetic process from pyruvate
regulation of glucose metabolic process
peptidyl-serine phosphorylation
peroxisome proliferator activated receptor signaling pathway
cellular response to glucose stimulus
cellular response to fatty acid
hypoxia-inducible factor-1alpha signaling pathway
regulation of reactive oxygen species metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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