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Product Details
17080-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PDLIM7 Fusion Protein Ag1334 (1-222 aa encoded by BC014521)
Conjugate
Form
Liquid
Concentration
0.15 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MDSFKVVLE GPAPWGFRLQ GGKDFNVPLS ISRLTPGGKA AQAGVAVGDW VLSIDGENAG SLTHIEAQNK IRACGERLSL GLSRAQPVQS KPQKASAPAA DPPRYTFAPS VSLNKTARPF GAPPPADSAP QQNGQPLRPL VPDASKQRLM ENTEDWRPRP GTGQSRSFRI LAHLTGTEFM QDPDEEHLKK SREKYVLELQ SPRYTRLRDW HHQRSAHVLN VQS (1-222 aa encoded by BC014521)
Target Information
The protein encoded by this gene is representative of a family of proteins composed of conserved PDZ and LIM domains. LIM domains are proposed to function in protein-protein recognition in a variety of contexts including gene transcription and development and in cytoskeletal interaction. The LIM domains of this protein bind to protein kinases, whereas the PDZ domain binds to actin filaments. The gene product is involved in the assembly of an actin filament-associated complex essential for transmission of ret/ptc2 mitogenic signaling. The biological function is likely to be that of an adapter, with the PDZ domain localizing the LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Alternative splicing of this gene results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 1110003B01Rik; enigma (LIM domain protein); LIM domain protein; LIM mineralization protein; LIM mineralization protein 2; Lim mineralization protein 3; LMP; PDZ and LIM domain 7 (enigma); PDZ and LIM domain protein 7; Protein enigma
Gene Aliases: ENIGMA; Lim1; LMP; LMP1; LMP3; PDLIM7
UniProt ID: (Human) Q9NR12, (Mouse) Q3TJD7, (Rat) Q9Z1Z9
Entrez Gene ID: (Human) 9260, (Mouse) 67399, (Rat) 286908
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