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PEA15 Antibody (MA5-47430) in IHC (PFA)
Immunohistochemistry analysis of PEA15 in rat brain section. Samples were stained with PEA15 monoclonal antibody (Product # MA5-47430) using a dilution of 1:1,000 (red). Costained with rabbit pAb to GFAP dilution 1:5,000 in green. The blue is Hoechst staining of nuclear DNA. Following transcardial perfusion of rat with 4% paraformaldehyde, brain was post fixed for 24 hours, cut to 45 μM, and free-floating s... View More
Product Details
MA5-47430
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
4D2
Immunogen
Full length human PEA-15 as expressed in and purified from E. coli.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A/G
Storage buffer
PBS with 50% glycerol
Contains
5mM sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2942412
Target Information
PEA15 is a death effector domain (DED)-containing protein predominantly expressed in the central nervous system, particularly in astrocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 15 kDa phosphoprotein enriched in astrocytes; Astrocytic phosphoprotein PEA-15; homolog of mouse MAT-1 oncogene; mammary transforming gene 1; mammary transforming gene 1, mouse, homolog of; OTTHUMP00000029887; PED; phosphoprotein enriched in astrocytes 15; phosphoprotein enriched in astrocytes 15A; Phosphoprotein enriched in diabetes
Gene Aliases: BOS_2644; HMAT1; HUMMAT1H; MAT1; MAT1H; PEA-15; PEA15; Pea15a; PED; Pkcs15
UniProt ID: (Human) Q15121, (Rat) Q5U318, (Mouse) Q62048
Entrez Gene ID: (Human) 8682, (Bovine) 510586, (Rat) 364052, (Mouse) 18611
DNA damage checkpoint
MAPK cascade
activation of MAPK activity
transport
apoptotic process
carbohydrate transport
response to morphine
negative regulation of glucose import
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
intracellular signal transduction
regulation of apoptotic process
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