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Invitrogen
PEO1 Polyclonal Antibody
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Product Details
PA5-51715
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human PEO1. Recombinant protein control fragment (Product #RP-102228).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2645385
Product Specific Information
Immunogen sequence: SKAPEFEDSE EVRRIWNRAI PLWELPDQEE VQLADTMFGL TKVTDDTLKR FSVRYLRPAR SLVFPWFSPG GSGLRGLKLL EAKCQGDGVS YEETTIPRPS AYHNLFGLPL ISRRDAEVVL TSRELDSLAL NQSTG
Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 78%.
Target Information
Twinkle is a mitochondrial protein with structural similarity to the phage T7 primase/helicase (GP4) and other hexameric ring helicases. The twinkle protein colocalizes with mtDNA in mitochondrial nucleoids, and its name derives from the unusual localization pattern reminiscent of twinkling stars.Twinkle is a mitochondrial protein with structural similarity to the phage T7 primase/helicase (GP4) and other hexameric ring helicases. The twinkle protein colocalizes with mtDNA in mitochondrial nucleoids, and its name derives from the unusual localization pattern reminiscent of twinkling stars (Spelbrink et al., 2001 [PubMed 11431692]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ataxin 8; Ataxin8; ATXN 8; C10 orf2; C10orf 2; FLJ21832; mitochondrial twinkle protein; PEO 1; Progressive external ophthalmoplegia 1 protein; SCA 8; T7 gp4-like protein with intramitochondrial nucleoid localization; T7 helicase-related protein with intramitochondrial nucleoid localization; T7-like mitochondrial DNA helicase; Twinkle mtDNA helicase; Twinkle protein, mitochondrial
Gene Aliases: ATXN8; C10orf2; IOSCA; MTDPS7; PEO; PEO1; PEOA3; PRLTS5; SANDO; SCA8; TWINL; TWNK
UniProt ID: (Human) Q96RR1
Entrez Gene ID: (Human) 56652
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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