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Bethyl Laboratories
PEX14 Polyclonal Antibody
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PEX14 Antibody (A303-086A) in WB
Detection of human PEX14 by western blot and immunoprecipitation. Samples: Whole cell lysate from HeLa (5, 15 and 50 µg for WB; 1 mg for IP, 20% of IP loaded) and HEK293T (T; 50 µg) cells. Antibodies: Affinity purified rabbit anti-PEX14 antibody (Product # A303-086A) used for WB at 0.04 µg/mL (A) and 1 µg/mL (B) and used for IP at 6 µg/mg lysate. PEX14 was also immunoprecipitated by rabbit anti-PEX14 antibody A303-085A, which recognizes an upstream epitope. Detection: Chemiluminescence with exposure times of 3 minutes (A) and 10 seconds (B... View More
Product Details
A303-086A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 327 and 377 of human Peroxisomal Biogenesis Factor 14.
Conjugate
Form
Liquid
Concentration
0.20 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.0 to 8.0, with 0.1% BSA
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Rat
Target Information
PEX14 belongs to the peroxin 14 family. It is a component of the peroxisomal translocation machinery with PEX13 and PEX17 and interacts with both the PTS1 and PTS2 receptors. PEX14 binds directly to PEX17. Defects in PEX14 are the cause of peroxisome biogenesis disorder complementation group K (PBD-CGK) and Zellweger syndrome (ZWS).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: NF-E2 associated polypeptide 2; Peroxin 14; Peroxin-14; Peroxisomal membrane anchor protein PEX14; peroxisomal membrane anchor protein Pex14p; Peroxisomal membrane protein PEX14; PEXE; PTS1 receptor docking protein; PTS1 receptor-docking protein
Gene Aliases: dJ734G22.2; NAPP2; PBD13A; PEX14; Pex14p
UniProt ID: (Human) O75381
Entrez Gene ID: (Human) 5195
protein complex assembly
peroxisome organization
protein import into peroxisome matrix
protein import into peroxisome matrix, translocation
negative regulation of protein binding
microtubule anchoring
peroxisome transport along microtubule
negative regulation of sequence-specific DNA binding transcription factor activity
protein import into peroxisome matrix, substrate release
negative regulation of transcription, DNA-templated
protein homooligomerization
negative regulation of protein homotetramerization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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