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This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Pex5l is an accessory subunit of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, regulating their cell-surface expression and cyclic nucleotide dependence. Research studies have shown that Pex5l is expressed in the brain, testis and pancreas. Diseases associated with PEX5L include Rhizomelic Chondrodysplasia Punctata, Type 5 and Rhizomelic Chondrodysplasia Punctata, Type 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: peroxin 2; Peroxin-5-related protein; peroxisomal targeting signal 1 receptor-like; PEX2-related protein; PEX5-like protein; PEX5-related protein; Pex5Rp; Tetratricopeptide repeat-containing Rab8b-interacting protein
Gene Aliases: 1700016J08Rik; Pex2; Pex5l; Pex5r; PXR2; TRIP8b
UniProt ID: (Mouse) Q8C437
Entrez Gene ID: (Mouse) 58869
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