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Antibody detects endogenous levels of total PEX6.
PEX6 encodes a member of the AAA (ATPases associated with diverse cellular activities) family of ATPases. This member is a predominantly cytoplasmic protein, which plays a direct role in peroxisomal protein import and is required for PTS1 (peroxisomal targeting signal 1, a C-terminal tripeptide of the sequence ser-lys-leu) receptor activity. Mutations in this gene cause peroxisome biogenesis disorders of complementation group 4 and complementation group 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: PAF 2; PAF-2; Peroxin 6; Peroxin-6; peroxisomal AAA-type ATPase 1; Peroxisomal ATPase PEX6; Peroxisomal biogenesis factor 6; Peroxisomal-type ATPase 1; Peroxisome assembly factor 2; RP1-125M3.3
Gene Aliases: AI132582; D130055I09Rik; HMLR2; mKIAA4177; PAF-2; PAF2; PBD4A; PDB4B; PEX6; PXAAA1
UniProt ID: (Human) Q13608, (Mouse) Q99LC9, (Rat) P54777
Entrez Gene ID: (Human) 5190, (Mouse) 224824, (Rat) 117265
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