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Invitrogen
PF4V1 Polyclonal Antibody
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Product Details
PA5-21944
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human PF4V1. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_11153400
Product Specific Information
Recommended positive controls: A431, H1299, HeLa, HepG2.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The PF4V1 (Platelet Factor 4 Variant 1) gene, located on chromosome 4q12, encodes a protein that is a member of the CXC chemokine family, sharing significant homology with platelet factor 4 (PF4/CXCL4). PF4V1 is primarily expressed in megakaryocytes and platelets, playing a role in modulating coagulation and inflammatory responses. The protein has chemotactic activity, attracting immune cells to sites of injury or inflammation. Furthermore, PF4V1 can bind to heparin, influencing the anticoagulant activity of heparin and potentially impacting hemostasis and thrombosis. Research suggests that variations in the expression or function of PF4V1 might contribute to different pathological conditions, including cardiovascular disease and inflammatory disorders.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: C-X-C motif chemokine 4; C-X-C motif chemokine 4 variant; CXCL4L1; PF4alt; PF4var1; Platelet factor 4 variant; platelet factor 4, variant 1 (PF4-like)
Gene Aliases: CXCL4L1; CXCL4V1; PF4-ALT; PF4A; PF4V1; SCYB4V1
UniProt ID: (Human) P10720
Entrez Gene ID: (Human) 5197
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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