Product References
Ectopic endometriotic stromal cells-derived lactate induces M2 macrophage polarization via Mettl3/Trib1/ERK/STAT3 signalling pathway in endometriosis.
Immunology
Gou Y,Wang H,Wang T,Wang H,Wang B,Jiao N,Yu Y,Cao Y,Wang H,Zhang Z
Wed Mar 01 00:00:00 UTC 2023
p38 MAPK and MKP-1 control the glycolytic program via the bifunctional glycolysis regulator PFKFB3 during sepsis.
The Journal of biological chemistry
Mager CE,Mormol JM,Shelton ED,Murphy PR,Bowman BA,Barley TJ,Wang X,Linn SC,Liu K,Nelin LD,Hafner M,Liu Y
Sat Apr 01 00:00:00 UTC 2023
Upregulation of glycolytic enzyme PFKFB3 by deubiquitinase OTUD4 promotes cardiac fibrosis post myocardial infarction.
Journal of molecular medicine (Berlin, Germany)
Wang F,Yin X,Fan YM,Zhang X,Ma C,Jia K,Zhou W,Tang Z,Qi LW,Li J
Thu Jun 01 00:00:00 UTC 2023
Garlic-derived exosomes carrying miR-396e shapes macrophage metabolic reprograming to mitigate the inflammatory response in obese adipose tissue.
The Journal of nutritional biochemistry
Bian Y,Li W,Jiang X,Yin F,Yin L,Zhang Y,Guo H,Liu J
Wed Mar 01 00:00:00 UTC 2023
PKM2-mediated neuronal hyperglycolysis enhances the risk of Parkinson's disease in diabetic rats.
Journal of pharmaceutical analysis
Zhao Y,Wang Y,Wu Y,Tao C,Xu R,Chen Y,Qian L,Xu T,Lian X
Wed Feb 01 00:00:00 UTC 2023
TMT-based quantitative proteomic analysis of spheroid cells of endometrial cancer possessing cancer stem cell properties.
Stem cell research & therapy
Cao M,Liu Z,You D,Pan Y,Zhang Q
Thu May 04 00:00:00 UTC 2023
Acetate controls endothelial-to-mesenchymal transition.
Cell metabolism
Zhu X,Wang Y,Soaita I,Lee HW,Bae H,Boutagy N,Bostwick A,Zhang RM,Bowman C,Xu Y,Trefely S,Chen Y,Qin L,Sessa W,Tellides G,Jang C,Snyder NW,Yu L,Arany Z,Simons M
Tue Jul 11 00:00:00 UTC 2023
Increased expression of 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase-3 is required for growth of mouse embryonic stem cells that are undergoing differentiation.
Cytotechnology
Guzel S,Gurpinar Y,Altunok TH,Yalcin A
Wed Feb 01 00:00:00 UTC 2023
Small extracellular vesicles derived from human adipose-derived stem cells regulate energetic metabolism through the activation of YAP/TAZ pathway facilitating angiogenesis.
Cell biology international
Sun J,Lin Z,Liao Z,Wu Z,Li H,Wang H
Wed Feb 01 00:00:00 UTC 2023
A glycometabolic gene signature associating with immune infiltration and chemosensitivity and predicting the prognosis of patients with osteosarcoma.
Frontiers in medicine
Wang F,Yang K,Pan R,Xiang Y,Xiong Z,Li P,Li K,Sun H
Mon Jun 12 00:00:00 UTC 2023
Andrographolide inhibits murine embryonic neuronal development through PFKFB3-mediated glycolytic pathway.
European journal of pharmacology
Shi L,Li H,Wang Z,Liu W,Wu X,Li J,Jin Z,Hu W,Guo Q,Zhang L,Wang Y,Liang B,Zhu S,Zhang H,Xu H,Yang L,Shi R,Wang Y
Sun Feb 05 00:00:00 UTC 2023
Andrographolide inhibits murine embryonic neuronal development through PFKFB3-mediated glycolytic pathway.
European journal of pharmacology
Shi L,Li H,Wang Z,Liu W,Wu X,Li J,Jin Z,Hu W,Guo Q,Zhang L,Wang Y,Liang B,Zhu S,Zhang H,Xu H,Yang L,Shi R,Wang Y
Sun Feb 05 00:00:00 UTC 2023
Andrographolide inhibits murine embryonic neuronal development through PFKFB3-mediated glycolytic pathway.
European journal of pharmacology
Shi L,Li H,Wang Z,Liu W,Wu X,Li J,Jin Z,Hu W,Guo Q,Zhang L,Wang Y,Liang B,Zhu S,Zhang H,Xu H,Yang L,Shi R,Wang Y
Sun Feb 05 00:00:00 UTC 2023
Andrographolide inhibits murine embryonic neuronal development through PFKFB3-mediated glycolytic pathway.
European journal of pharmacology
Shi L,Li H,Wang Z,Liu W,Wu X,Li J,Jin Z,Hu W,Guo Q,Zhang L,Wang Y,Liang B,Zhu S,Zhang H,Xu H,Yang L,Shi R,Wang Y
Sun Feb 05 00:00:00 UTC 2023
Andrographolide inhibits murine embryonic neuronal development through PFKFB3-mediated glycolytic pathway.
European journal of pharmacology
Shi L,Li H,Wang Z,Liu W,Wu X,Li J,Jin Z,Hu W,Guo Q,Zhang L,Wang Y,Liang B,Zhu S,Zhang H,Xu H,Yang L,Shi R,Wang Y
Sun Feb 05 00:00:00 UTC 2023
Andrographolide inhibits murine embryonic neuronal development through PFKFB3-mediated glycolytic pathway.
European journal of pharmacology
Shi L,Li H,Wang Z,Liu W,Wu X,Li J,Jin Z,Hu W,Guo Q,Zhang L,Wang Y,Liang B,Zhu S,Zhang H,Xu H,Yang L,Shi R,Wang Y
Sun Feb 05 00:00:00 UTC 2023
Piezo1 channel activation stimulates ATP production through enhancing mitochondrial respiration and glycolysis in vascular endothelial cells.
British journal of pharmacology
Jiang M,Zhang YX,Bu WJ,Li P,Chen JH,Cao M,Dong YC,Sun ZJ,Dong DL
Sat Jul 01 00:00:00 UTC 2023
Evaluation of Mitochondrial Function in Blood Samples Shows Distinct Patterns in Subjects with Thyroid Carcinoma from Those with Hyperplasia.
International journal of molecular sciences
Bernal-Tirapo J,Bayo Jiménez MT,Yuste-García P,Cordova I,Peñas A,García-Borda FJ,Quintela C,Prieto I,Sánchez-Ramos C,Ferrero-Herrero E,Monsalve M
Wed Mar 29 00:00:00 UTC 2023
Prognosis-related molecular subtyping in head and neck squamous cell carcinoma patients based on glycolytic/cholesterogenic gene data.
Cancer cell international
Zhou Z,Tang J,Lu Y,Jia J,Luo T,Su K,Dai X,Zhang H,Liu O
Sat Feb 25 00:00:00 UTC 2023
Enhancement of glycolysis-dependent DNA repair regulated by FOXO1 knockdown via PFKFB3 attenuates hyperglycemia-induced endothelial oxidative stress injury.
Redox biology
Sun D,Chen S,Li S,Wang N,Zhang S,Xu L,Zhu S,Li H,Gu Q,Xu X,Wei F
Wed Feb 01 00:00:00 UTC 2023
Enhancement of glycolysis-dependent DNA repair regulated by FOXO1 knockdown via PFKFB3 attenuates hyperglycemia-induced endothelial oxidative stress injury.
Redox biology
Sun D,Chen S,Li S,Wang N,Zhang S,Xu L,Zhu S,Li H,Gu Q,Xu X,Wei F
Wed Feb 01 00:00:00 UTC 2023
Enhancement of glycolysis-dependent DNA repair regulated by FOXO1 knockdown via PFKFB3 attenuates hyperglycemia-induced endothelial oxidative stress injury.
Redox biology
Sun D,Chen S,Li S,Wang N,Zhang S,Xu L,Zhu S,Li H,Gu Q,Xu X,Wei F
Wed Feb 01 00:00:00 UTC 2023
Enhancement of glycolysis-dependent DNA repair regulated by FOXO1 knockdown via PFKFB3 attenuates hyperglycemia-induced endothelial oxidative stress injury.
Redox biology
Sun D,Chen S,Li S,Wang N,Zhang S,Xu L,Zhu S,Li H,Gu Q,Xu X,Wei F
Wed Feb 01 00:00:00 UTC 2023
Disruption of COMMD1 accelerates diabetic atherosclerosis by promoting glycolysis.
Diabetes & vascular disease research
Zhang L,Li L,Li Y,Jiang H,Sun Z,Zang G,Qian Y,Shao C,Wang Z
Thu Feb 23 00:00:00 UTC 2023
Blockage of glycolysis by targeting PFKFB3 suppresses the development of infantile hemangioma.
Journal of translational medicine
Yang K,Qiu T,Zhou J,Gong X,Zhang X,Lan Y,Zhang Z,Ji Y
Mon Feb 06 00:00:00 UTC 2023
Blockage of glycolysis by targeting PFKFB3 suppresses the development of infantile hemangioma.
Journal of translational medicine
Yang K,Qiu T,Zhou J,Gong X,Zhang X,Lan Y,Zhang Z,Ji Y
Mon Feb 06 00:00:00 UTC 2023
Blockage of glycolysis by targeting PFKFB3 suppresses the development of infantile hemangioma.
Journal of translational medicine
Yang K,Qiu T,Zhou J,Gong X,Zhang X,Lan Y,Zhang Z,Ji Y
Mon Feb 06 00:00:00 UTC 2023
Blockage of glycolysis by targeting PFKFB3 suppresses the development of infantile hemangioma.
Journal of translational medicine
Yang K,Qiu T,Zhou J,Gong X,Zhang X,Lan Y,Zhang Z,Ji Y
Mon Feb 06 00:00:00 UTC 2023
Iso-seco-tanapartholide from Artemisia argyi inhibits the PFKFB3-mediated glycolytic pathway to attenuate airway inflammation in lipopolysaccharide-induced acute lung injury mice.
Journal of ethnopharmacology
Kong M,Zhu D,Dong J,Kong L,Luo J
Mon Jan 30 00:00:00 UTC 2023
Iso-seco-tanapartholide from Artemisia argyi inhibits the PFKFB3-mediated glycolytic pathway to attenuate airway inflammation in lipopolysaccharide-induced acute lung injury mice.
Journal of ethnopharmacology
Kong M,Zhu D,Dong J,Kong L,Luo J
Mon Jan 30 00:00:00 UTC 2023
Iso-seco-tanapartholide from Artemisia argyi inhibits the PFKFB3-mediated glycolytic pathway to attenuate airway inflammation in lipopolysaccharide-induced acute lung injury mice.
Journal of ethnopharmacology
Kong M,Zhu D,Dong J,Kong L,Luo J
Mon Jan 30 00:00:00 UTC 2023
Hyperglycemia induces PFKFB3 overexpression and promotes malignant phenotype of breast cancer through RAS/MAPK activation.
World journal of surgical oncology
Cheng X,Jia X,Wang C,Zhou S,Chen J,Chen L,Chen J
Tue Mar 28 00:00:00 UTC 2023
Hyperglycemia induces PFKFB3 overexpression and promotes malignant phenotype of breast cancer through RAS/MAPK activation.
World journal of surgical oncology
Cheng X,Jia X,Wang C,Zhou S,Chen J,Chen L,Chen J
Tue Mar 28 00:00:00 UTC 2023
Garlic-derived exosomes regulate PFKFB3 expression to relieve liver dysfunction in high-fat diet-fed mice via macrophage-hepatocyte crosstalk.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Liu J,Li W,Bian Y,Jiang X,Zhu F,Yin F,Yin L,Song X,Guo H,Liu J
Sat Apr 01 00:00:00 UTC 2023
Circular RNA circ-FoxO3 attenuates blood-brain barrier damage by inducing autophagy during ischemia/reperfusion.
Molecular therapy : the journal of the American Society of Gene Therapy
Yang Z,Huang C,Wen X,Liu W,Huang X,Li Y,Zang J,Weng Z,Lu D,Tsang CK,Li K,Xu A
Wed Mar 02 00:00:00 UTC 2022
Metabolism-Based Molecular Subtyping Endows Effective Ketogenic Therapy in p53-Mutant Colon Cancer.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Tang M,Xu H,Huang H,Kuang H,Wang C,Li Q,Zhang X,Ge Y,Song M,Zhang X,Wang Z,Ma C,Kang J,Zhang W,Wang Y,Zhang B,Zhang X,Chen Y,Cong M,Melino G,Wang X,Zhou F,Sun Q,Shi H
Sat Oct 01 00:00:00 UTC 2022
Metabolism-Based Molecular Subtyping Endows Effective Ketogenic Therapy in p53-Mutant Colon Cancer.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Tang M,Xu H,Huang H,Kuang H,Wang C,Li Q,Zhang X,Ge Y,Song M,Zhang X,Wang Z,Ma C,Kang J,Zhang W,Wang Y,Zhang B,Zhang X,Chen Y,Cong M,Melino G,Wang X,Zhou F,Sun Q,Shi H
Sat Oct 01 00:00:00 UTC 2022
AAV-mediated expression of PFKFB3 in myofibers, but not endothelial cells, improves ischemic muscle function in mice with critical limb ischemia.
American journal of physiology. Heart and circulatory physiology
Salyers ZR,Coleman M,Le D,Ryan TE
Thu Sep 01 00:00:00 UTC 2022
BRAF activation by metabolic stress promotes glycolysis sensitizing NRASQ61-mutated melanomas to targeted therapy.
Nature communications
McGrail K,Granado-Martínez P,Esteve-Puig R,García-Ortega S,Ding Y,Sánchez-Redondo S,Ferrer B,Hernandez-Losa J,Canals F,Manzano A,Navarro-Sabaté A,Bartrons R,Yanes O,Pérez-Alea M,Muñoz-Couselo E,Garcia-Patos V,Recio JA
Sat Nov 19 00:00:00 UTC 2022
BRAF activation by metabolic stress promotes glycolysis sensitizing NRASQ61-mutated melanomas to targeted therapy.
Nature communications
McGrail K,Granado-Martínez P,Esteve-Puig R,García-Ortega S,Ding Y,Sánchez-Redondo S,Ferrer B,Hernandez-Losa J,Canals F,Manzano A,Navarro-Sabaté A,Bartrons R,Yanes O,Pérez-Alea M,Muñoz-Couselo E,Garcia-Patos V,Recio JA
Sat Nov 19 00:00:00 UTC 2022
BRAF activation by metabolic stress promotes glycolysis sensitizing NRASQ61-mutated melanomas to targeted therapy.
Nature communications
McGrail K,Granado-Martínez P,Esteve-Puig R,García-Ortega S,Ding Y,Sánchez-Redondo S,Ferrer B,Hernandez-Losa J,Canals F,Manzano A,Navarro-Sabaté A,Bartrons R,Yanes O,Pérez-Alea M,Muñoz-Couselo E,Garcia-Patos V,Recio JA
Sat Nov 19 00:00:00 UTC 2022
Integrated metabolism and epigenetic modifications in the macrophages of mice in responses to cold stress.
Journal of Zhejiang University. Science. B
Lu J,Fu S,Dai J,Hu J,Li S,Ji H,Wang Z,Yu J,Bao J,Xu B,Guo J,Yang H
Wed Jun 15 00:00:00 UTC 2022
Hyperglycemia induces miR-26-5p down-regulation to overexpress PFKFB3 and accelerate epithelial-mesenchymal transition in gastric cancer.
Bioengineered
He X,Cheng X,Ding J,Xiong M,Chen B,Cao G
Tue Feb 01 00:00:00 UTC 2022
Hyperglycemia induces miR-26-5p down-regulation to overexpress PFKFB3 and accelerate epithelial-mesenchymal transition in gastric cancer.
Bioengineered
He X,Cheng X,Ding J,Xiong M,Chen B,Cao G
Tue Feb 01 00:00:00 UTC 2022
Newcastle disease virus degrades SIRT3 via PINK1-PRKN-dependent mitophagy to reprogram energy metabolism in infected cells.
Autophagy
Gong Y,Tang N,Liu P,Sun Y,Lu S,Liu W,Tan L,Song C,Qiu X,Liao Y,Yu S,Liu X,Lin SH,Ding C
Fri Jul 01 00:00:00 UTC 2022
Monosodium urate crystals regulate a unique JNK-dependent macrophage metabolic and inflammatory response.
Cell reports
Cobo I,Cheng A,Murillo-Saich J,Coras R,Torres A,Abe Y,Lana AJ,Schlachetzki J,Liu-Bryan R,Terkeltaub R,Sanchez-Lopez E,Glass CK,Guma M
Tue Mar 08 00:00:00 UTC 2022
Monosodium urate crystals regulate a unique JNK-dependent macrophage metabolic and inflammatory response.
Cell reports
Cobo I,Cheng A,Murillo-Saich J,Coras R,Torres A,Abe Y,Lana AJ,Schlachetzki J,Liu-Bryan R,Terkeltaub R,Sanchez-Lopez E,Glass CK,Guma M
Tue Mar 08 00:00:00 UTC 2022
Disrupting Circadian Rhythm via the PER1-HK2 Axis Reverses Trastuzumab Resistance in Gastric Cancer.
Cancer research
Wang J,Huang Q,Hu X,Zhang S,Jiang Y,Yao G,Hu K,Xu X,Liang B,Wu Q,Ma Z,Wang Y,Wang C,Wu Z,Rong X,Liao W,Shi M
Fri Apr 15 00:00:00 UTC 2022
Polarization and β-Glucan Reprogram Immunomodulatory Metabolism in Human Macrophages and Ex Vivo in Human Lung Cancer Tissues.
Journal of immunology (Baltimore, Md. : 1950)
Fan TW,Daneshmandi S,Cassel TA,Uddin MB,Sledziona J,Thompson PT,Lin P,Higashi RM,Lane AN
Tue Nov 01 00:00:00 UTC 2022
Candida tropicalis induces NLRP3 inflammasome activation via glycogen metabolism-dependent glycolysis and JAK-STAT1 signaling pathway in myeloid-derived suppressor cells to promote colorectal carcinogenesis.
International immunopharmacology
Zhang Z,Chen Y,Yin Y,Chen Y,Chen Q,Bing Z,Zheng Y,Hou Y,Shen S,Chen Y,Wang T
Thu Dec 01 00:00:00 UTC 2022
Moderate heart rate reduction promotes cardiac regeneration through stimulation of the metabolic pattern switch.
Cell reports
Tan J,Yang M,Wang H,Shen C,Wu M,Xu H,Wu Y,Li Y,Li X,Huang T,Deng S,Yang Z,Gao S,Li H,Zhou J,Chen H,Cao N,Cai W
Tue Mar 08 00:00:00 UTC 2022
CYLD deficiency enhances metabolic reprogramming and tumor progression in nasopharyngeal carcinoma via PFKFB3.
Cancer letters
Wang L,Lin Y,Zhou X,Chen Y,Li X,Luo W,Zhou Y,Cai L
Thu Apr 28 00:00:00 UTC 2022
IGFBP5 promotes diabetic kidney disease progression by enhancing PFKFB3-mediated endothelial glycolysis.
Cell death & disease
Song C,Wang S,Fu Z,Chi K,Geng X,Liu C,Cai G,Chen X,Wu D,Hong Q
Wed Apr 13 00:00:00 UTC 2022
Dendropanax trifidus Sap-Mediated Suppression of Obese Mouse Body Weight and the Metabolic Changes Related with Estrogen Receptor Alpha and AMPK-ACC Pathways in Muscle Cells.
Nutrients
Lee A,Koh E,Kim D,Lee N,Cho SM,Lee YJ,Cho IH,Yang HJ
Sat Mar 05 00:00:00 UTC 2022
ALK fusion promotes metabolic reprogramming of cancer cells by transcriptionally upregulating PFKFB3.
Oncogene
Hu M,Bao R,Lin M,Han XR,Ai YJ,Gao Y,Guan KL,Xiong Y,Yuan HX
Thu Sep 01 00:00:00 UTC 2022
ALK fusion promotes metabolic reprogramming of cancer cells by transcriptionally upregulating PFKFB3.
Oncogene
Hu M,Bao R,Lin M,Han XR,Ai YJ,Gao Y,Guan KL,Xiong Y,Yuan HX
Thu Sep 01 00:00:00 UTC 2022
Placenta-Targeted Nanoparticles Loaded with PFKFB3 Overexpression Plasmids Enhance Angiogenesis and Placental Function.
Bioengineering (Basel, Switzerland)
Li Q,Liu X,Liu W,Zhang Y,Liu W,Wu M,Chen Z,Zhao Y,Zou L
Fri Nov 04 00:00:00 UTC 2022
Placenta-Targeted Nanoparticles Loaded with PFKFB3 Overexpression Plasmids Enhance Angiogenesis and Placental Function.
Bioengineering (Basel, Switzerland)
Li Q,Liu X,Liu W,Zhang Y,Liu W,Wu M,Chen Z,Zhao Y,Zou L
Fri Nov 04 00:00:00 UTC 2022
Inhibition of PFKFB3 in HER2-positive gastric cancer improves sensitivity to trastuzumab by inducing tumour vessel normalisation.
British journal of cancer
Yao X,He Z,Qin C,Zhang P,Sui C,Deng X,Fang Y,Li G,Shi J
Thu Sep 01 00:00:00 UTC 2022
Inhibition of PFKFB3 in HER2-positive gastric cancer improves sensitivity to trastuzumab by inducing tumour vessel normalisation.
British journal of cancer
Yao X,He Z,Qin C,Zhang P,Sui C,Deng X,Fang Y,Li G,Shi J
Thu Sep 01 00:00:00 UTC 2022
Inhibition of PFKFB3 in HER2-positive gastric cancer improves sensitivity to trastuzumab by inducing tumour vessel normalisation.
British journal of cancer
Yao X,He Z,Qin C,Zhang P,Sui C,Deng X,Fang Y,Li G,Shi J
Thu Sep 01 00:00:00 UTC 2022
Inhibition of PFKFB3 in HER2-positive gastric cancer improves sensitivity to trastuzumab by inducing tumour vessel normalisation.
British journal of cancer
Yao X,He Z,Qin C,Zhang P,Sui C,Deng X,Fang Y,Li G,Shi J
Thu Sep 01 00:00:00 UTC 2022
Cryptotanshinone attenuates LPS-induced acute lung injury by regulating metabolic reprogramming of macrophage.
Frontiers in medicine
Ye Z,Wang P,Feng G,Wang Q,Liu C,Lu J,Chen J,Liu P
Thu Feb 02 00:00:00 UTC 2023
Increased stromal PFKFB3-mediated glycolysis in inflammatory bowel disease contributes to intestinal inflammation.
Frontiers in immunology
Zhou Z,Plug LG,Patente TA,de Jonge-Muller ESM,Elmagd AA,van der Meulen-de Jong AE,Everts B,Barnhoorn MC,Hawinkels LJAC
Tue Nov 22 00:00:00 UTC 2022
Increased stromal PFKFB3-mediated glycolysis in inflammatory bowel disease contributes to intestinal inflammation.
Frontiers in immunology
Zhou Z,Plug LG,Patente TA,de Jonge-Muller ESM,Elmagd AA,van der Meulen-de Jong AE,Everts B,Barnhoorn MC,Hawinkels LJAC
Tue Nov 22 00:00:00 UTC 2022
Increased stromal PFKFB3-mediated glycolysis in inflammatory bowel disease contributes to intestinal inflammation.
Frontiers in immunology
Zhou Z,Plug LG,Patente TA,de Jonge-Muller ESM,Elmagd AA,van der Meulen-de Jong AE,Everts B,Barnhoorn MC,Hawinkels LJAC
Tue Nov 22 00:00:00 UTC 2022
MiR-652-5p elevated glycolysis level by targeting TIGAR in T-cell acute lymphoblastic leukemia.
Cell death & disease
Liu S,Wang H,Guo W,Zhou X,Shu Y,Liu H,Yang L,Tang S,Su H,Liu Z,Zeng L,Zou L
Mon Feb 14 00:00:00 UTC 2022
Berberine Modulates Macrophage Activation by Inducing Glycolysis.
Journal of immunology (Baltimore, Md. : 1950)
Li M,Zhang H,Zhang Y,Fan J,Zhu J,Gu X,Li Z,Zhang C,Liu Z,Li Y,Zang M,Jin G,Li G,Mi Y
Sun May 15 00:00:00 UTC 2022
PFKFB3 Inhibition Sensitizes DNA Crosslinking Chemotherapies by Suppressing Fanconi Anemia Repair.
Cancers
Ninou AH,Lehto J,Chioureas D,Stigsdotter H,Schelzig K,Åkerlund E,Gudoityte G,Joneborg U,Carlson J,Jonkers J,Seashore-Ludlow B,Gustafsson NMS
Sun Jul 18 00:00:00 UTC 2021
PKM2 Is the Target of a Multi-Herb-Combined Decoction During the Inhibition of Gastric Cancer Progression.
Frontiers in oncology
Sun Q,Yuan M,Wang H,Zhang X,Zhang R,Wang H,Chen X,Zhu M,Liu S,Wu J
Fri Apr 29 00:00:00 UTC 2022
PFKFB3 regulates lipopolysaccharide-induced excessive inflammation and cellular dysfunction in HTR-8/Svneo cells: Implications for the role of PFKFB3 in preeclampsia.
Placenta
Zhang Y,Liu W,Wu M,Li Q,Liu Y,Yang L,Chen Y,Zhong Y,Liu X,Zou L
Mon Mar 01 00:00:00 UTC 2021
PFKFB3 regulates lipopolysaccharide-induced excessive inflammation and cellular dysfunction in HTR-8/Svneo cells: Implications for the role of PFKFB3 in preeclampsia.
Placenta
Zhang Y,Liu W,Wu M,Li Q,Liu Y,Yang L,Chen Y,Zhong Y,Liu X,Zou L
Mon Mar 01 00:00:00 UTC 2021
NEAT1 is essential for metabolic changes that promote breast cancer growth and metastasis.
Cell metabolism
Park MK,Zhang L,Min KW,Cho JH,Yeh CC,Moon H,Hormaechea-Agulla D,Mun H,Ko S,Lee JW,Jathar S,Smith AS,Yao Y,Giang NT,Vu HH,Yan VC,Bridges MC,Kourtidis A,Muller F,Chang JH,Song SJ,Nakagawa S,Hirose T,Yoon JH,Song MS
Tue Dec 07 00:00:00 UTC 2021
Sex differences in metabolic pathways are regulated by Pfkfb3 and Pdk4 expression in rodent muscle.
Communications biology
Christianto A,Baba T,Takahashi F,Inui K,Inoue M,Suyama M,Ono Y,Ohkawa Y,Morohashi KI
Thu Nov 04 00:00:00 UTC 2021
MALAT1 sponges miR-26a and miR-26b to regulate endothelial cell angiogenesis via PFKFB3-driven glycolysis in early-onset preeclampsia.
Molecular therapy. Nucleic acids
Li Q,Liu X,Liu W,Zhang Y,Wu M,Chen Z,Zhao Y,Zou L
Fri Mar 05 00:00:00 UTC 2021
MALAT1 sponges miR-26a and miR-26b to regulate endothelial cell angiogenesis via PFKFB3-driven glycolysis in early-onset preeclampsia.
Molecular therapy. Nucleic acids
Li Q,Liu X,Liu W,Zhang Y,Wu M,Chen Z,Zhao Y,Zou L
Fri Mar 05 00:00:00 UTC 2021
Metformin Corrects Glucose Metabolism Reprogramming and NLRP3 Inflammasome-Induced Pyroptosis via Inhibiting the TLR4/NF-κB/PFKFB3 Signaling in Trophoblasts: Implication for a Potential Therapy of Preeclampsia.
Oxidative medicine and cellular longevity
Zhang Y,Liu W,Zhong Y,Li Q,Wu M,Yang L,Liu X,Zou L
Tue Feb 08 00:00:00 UTC 2022
Metformin Corrects Glucose Metabolism Reprogramming and NLRP3 Inflammasome-Induced Pyroptosis via Inhibiting the TLR4/NF-κB/PFKFB3 Signaling in Trophoblasts: Implication for a Potential Therapy of Preeclampsia.
Oxidative medicine and cellular longevity
Zhang Y,Liu W,Zhong Y,Li Q,Wu M,Yang L,Liu X,Zou L
Tue Feb 08 00:00:00 UTC 2022
Dual Inhibition of Endoplasmic Reticulum Stress and Oxidation Stress Manipulates the Polarization of Macrophages under Hypoxia to Sensitize Immunotherapy.
ACS nano
Jiang M,Li X,Zhang J,Lu Y,Shi Y,Zhu C,Liu Y,Qin B,Luo Z,Du Y,Luo L,Peng L,You J
Tue Sep 28 00:00:00 UTC 2021
Prkaa1 Metabolically Regulates Monocyte/Macrophage Recruitment and Viability in Diet-Induced Murine Metabolic Disorders.
Frontiers in cell and developmental biology
Yang Q,Ma Q,Xu J,Liu Z,Zou J,Shen J,Zhou Y,Da Q,Mao X,Lu S,Fulton DJ,Weintraub NL,Bagi Z,Hong M,Huo Y
Sun Mar 31 00:00:00 UTC 2024
Inhibition of PFKFB3 suppresses osteoclastogenesis and prevents ovariectomy-induced bone loss.
Journal of cellular and molecular medicine
Wang J,Guan H,Liu H,Lei Z,Kang H,Guo Q,Dong Y,Liu H,Sun Y,Fang Z,Li F
Sat Feb 01 00:00:00 UTC 2020
Inhibition of PFKFB3 suppresses osteoclastogenesis and prevents ovariectomy-induced bone loss.
Journal of cellular and molecular medicine
Wang J,Guan H,Liu H,Lei Z,Kang H,Guo Q,Dong Y,Liu H,Sun Y,Fang Z,Li F
Sat Feb 01 00:00:00 UTC 2020
PFKFB2 regulates glycolysis and proliferation in pancreatic cancer cells.
Molecular and cellular biochemistry
Ozcan SC,Sarioglu A,Altunok TH,Akkoc A,Guzel S,Guler S,Imbert-Fernandez Y,Muchut RJ,Iglesias AA,Gurpinar Y,Clem AL,Chesney JA,Yalcin A
Wed Jul 01 00:00:00 UTC 2020
Inhibition of eNOS by L-NAME resulting in rat hind limb developmental defects through PFKFB3 mediated angiogenetic pathway.
Scientific reports
Wu Z,Yao H,Xu H,Wang Y,Hu W,Lou G,Zhang L,Huang C,Jiang C,Zhou S,Shi Y,Chen X,Yang L,Xu Y,Wang Y
Wed Oct 07 00:00:00 UTC 2020
Inhibition of eNOS by L-NAME resulting in rat hind limb developmental defects through PFKFB3 mediated angiogenetic pathway.
Scientific reports
Wu Z,Yao H,Xu H,Wang Y,Hu W,Lou G,Zhang L,Huang C,Jiang C,Zhou S,Shi Y,Chen X,Yang L,Xu Y,Wang Y
Wed Oct 07 00:00:00 UTC 2020
Inhibition of eNOS by L-NAME resulting in rat hind limb developmental defects through PFKFB3 mediated angiogenetic pathway.
Scientific reports
Wu Z,Yao H,Xu H,Wang Y,Hu W,Lou G,Zhang L,Huang C,Jiang C,Zhou S,Shi Y,Chen X,Yang L,Xu Y,Wang Y
Wed Oct 07 00:00:00 UTC 2020
Tissue-Resident Alveolar Macrophages Do Not Rely on Glycolysis for LPS-induced Inflammation.
American journal of respiratory cell and molecular biology
Woods PS,Kimmig LM,Meliton AY,Sun KA,Tian Y,O'Leary EM,Gökalp GA,Hamanaka RB,Mutlu GM
Sat Feb 01 00:00:00 UTC 2020
Fenofibrate-induced mitochondrial dysfunction and metabolic reprogramming reversal: the anti-tumor effects in gastric carcinoma cells mediated by the PPAR pathway.
American journal of translational research
Chen L,Peng J,Wang Y,Jiang H,Wang W,Dai J,Tang M,Wei Y,Kuang H,Xu G,Xu H,Zhou F
Thu Mar 28 00:00:00 UTC 2024
TAB1 regulates glycolysis and activation of macrophages in diabetic nephropathy.
Inflammation research : official journal of the European Histamine Research Society ... [et al.]
Zeng H,Qi X,Xu X,Wu Y
Tue Dec 01 00:00:00 UTC 2020
Metabolic adaptations in spontaneously immortalized PGC-1α knock-out mouse embryonic fibroblasts increase their oncogenic potential.
Redox biology
Prieto I,Alarcón CR,García-Gómez R,Berdún R,Urgel T,Portero M,Pamplona R,Martínez-Ruiz A,Ruiz-Sanz JI,Ruiz-Larrea MB,Jove M,Cerdán S,Monsalve M
Wed Jan 01 00:00:00 UTC 2020
Zhx2 Accelerates Sepsis by Promoting Macrophage Glycolysis via Pfkfb3.
Journal of immunology (Baltimore, Md. : 1950)
Wang Z,Kong L,Tan S,Zhang Y,Song X,Wang T,Lin Q,Wu Z,Xiang P,Li C,Gao L,Liang X,Ma C
Wed Apr 15 00:00:00 UTC 2020
The Glycolytic Enzyme PFKFB3 Controls TNF-α-Induced Endothelial Proinflammatory Responses.
Inflammation
Zhang R,Li R,Liu Y,Li L,Tang Y
Fri Feb 01 00:00:00 UTC 2019
The Glycolytic Enzyme PFKFB3 Controls TNF-α-Induced Endothelial Proinflammatory Responses.
Inflammation
Zhang R,Li R,Liu Y,Li L,Tang Y
Fri Feb 01 00:00:00 UTC 2019
Deoxyelephantopin suppresses hepatic stellate cells activation associated with inhibition of aerobic glycolysis via hedgehog pathway.
Biochemical and biophysical research communications
Gao W,Sun J,Wang F,Lu Y,Wen C,Bian Q,Wu H
Tue Sep 03 00:00:00 UTC 2019
Increased 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 activity in response to EGFR signaling contributes to non-small cell lung cancer cell survival.
The Journal of biological chemistry
Lypova N,Telang S,Chesney J,Imbert-Fernandez Y
Fri Jul 05 00:00:00 UTC 2019
Monocarboxylate transporter 1 promotes classical microglial activation and pro-inflammatory effect via 6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 3.
Journal of neuroinflammation
Kong L,Wang Z,Liang X,Wang Y,Gao L,Ma C
Thu Nov 28 00:00:00 UTC 2019
PFKFB3/HIF-1α feedback loop modulates sorafenib resistance in hepatocellular carcinoma cells.
Biochemical and biophysical research communications
Long Q,Zou X,Song Y,Duan Z,Liu L
Tue Jun 04 00:00:00 UTC 2019
Phostine 3.1a as a pharmacological compound with antiangiogenic properties against diseases with excess vascularization.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Bousseau S,Marchand M,Soleti R,Vergori L,Hilairet G,Recoquillon S,Le Mao M,Gueguen N,Khiati S,Clarion L,Bakalara N,Martinez MC,Germain S,Lenaers G,Andriantsitohaina R
Wed May 01 00:00:00 UTC 2019
Phosphofructokinases Axis Controls Glucose-Dependent mTORC1 Activation Driven by E2F1.
iScience
Almacellas E,Pelletier J,Manzano A,Gentilella A,Ambrosio S,Mauvezin C,Tauler A
Fri Oct 25 00:00:00 UTC 2019
PFKFB3 in Smooth Muscle Promotes Vascular Remodeling in Pulmonary Arterial Hypertension.
American journal of respiratory and critical care medicine
Kovacs L,Cao Y,Han W,Meadows L,Kovacs-Kasa A,Kondrikov D,Verin AD,Barman SA,Dong Z,Huo Y,Su Y
Sun Sep 01 00:00:00 UTC 2019
PFKFB3 in Smooth Muscle Promotes Vascular Remodeling in Pulmonary Arterial Hypertension.
American journal of respiratory and critical care medicine
Kovacs L,Cao Y,Han W,Meadows L,Kovacs-Kasa A,Kondrikov D,Verin AD,Barman SA,Dong Z,Huo Y,Su Y
Sun Sep 01 00:00:00 UTC 2019
PFKFB3 in Smooth Muscle Promotes Vascular Remodeling in Pulmonary Arterial Hypertension.
American journal of respiratory and critical care medicine
Kovacs L,Cao Y,Han W,Meadows L,Kovacs-Kasa A,Kondrikov D,Verin AD,Barman SA,Dong Z,Huo Y,Su Y
Sun Sep 01 00:00:00 UTC 2019
PFKFB3 in Smooth Muscle Promotes Vascular Remodeling in Pulmonary Arterial Hypertension.
American journal of respiratory and critical care medicine
Kovacs L,Cao Y,Han W,Meadows L,Kovacs-Kasa A,Kondrikov D,Verin AD,Barman SA,Dong Z,Huo Y,Su Y
Sun Sep 01 00:00:00 UTC 2019
PFKFB3 promotes endotoxemia-induced myocardial dysfunction through inflammatory signaling and apoptotic induction.
Toxicology and applied pharmacology
Tian W,Guo HS,Li CY,Cao W,Wang XY,Mo D,Hao XW,Feng YD,Sun Y,Lei F,Zhang HN,Zhao MG,Li XQ
Mon Apr 01 00:00:00 UTC 2019
PFKFB3 promotes endotoxemia-induced myocardial dysfunction through inflammatory signaling and apoptotic induction.
Toxicology and applied pharmacology
Tian W,Guo HS,Li CY,Cao W,Wang XY,Mo D,Hao XW,Feng YD,Sun Y,Lei F,Zhang HN,Zhao MG,Li XQ
Mon Apr 01 00:00:00 UTC 2019
PFKFB3 promotes endotoxemia-induced myocardial dysfunction through inflammatory signaling and apoptotic induction.
Toxicology and applied pharmacology
Tian W,Guo HS,Li CY,Cao W,Wang XY,Mo D,Hao XW,Feng YD,Sun Y,Lei F,Zhang HN,Zhao MG,Li XQ
Mon Apr 01 00:00:00 UTC 2019
CircACC1 Regulates Assembly and Activation of AMPK Complex under Metabolic Stress.
Cell metabolism
Li Q,Wang Y,Wu S,Zhou Z,Ding X,Shi R,Thorne RF,Zhang XD,Hu W,Wu M
Tue Jul 02 00:00:00 UTC 2019
PFKFB3 Inhibition Attenuates Oxaliplatin-Induced Autophagy and Enhances Its Cytotoxicity in Colon Cancer Cells.
International journal of molecular sciences
Yan S,Zhou N,Zhang D,Zhang K,Zheng W,Bao Y,Yang W
Wed Oct 30 00:00:00 UTC 2019
Andrographolide attenuates imbalance of gastric vascular homeostasis induced by ethanol through glycolysis pathway.
Scientific reports
Yao H,Wu Z,Xu Y,Xu H,Lou G,Jiang Q,Fan W,Liu W,Zheng C,Gao Y,Wang Y
Thu Mar 21 00:00:00 UTC 2019
Targeting PFKFB3 radiosensitizes cancer cells and suppresses homologous recombination.
Nature communications
Gustafsson NMS,Färnegårdh K,Bonagas N,Ninou AH,Groth P,Wiita E,Jönsson M,Hallberg K,Lehto J,Pennisi R,Martinsson J,Norström C,Hollers J,Schultz J,Andersson M,Markova N,Marttila P,Kim B,Norin M,Olin T,Helleday T
Mon Sep 24 00:00:00 UTC 2018
Targeting PFKFB3 radiosensitizes cancer cells and suppresses homologous recombination.
Nature communications
Gustafsson NMS,Färnegårdh K,Bonagas N,Ninou AH,Groth P,Wiita E,Jönsson M,Hallberg K,Lehto J,Pennisi R,Martinsson J,Norström C,Hollers J,Schultz J,Andersson M,Markova N,Marttila P,Kim B,Norin M,Olin T,Helleday T
Mon Sep 24 00:00:00 UTC 2018
Targeting PFKFB3 radiosensitizes cancer cells and suppresses homologous recombination.
Nature communications
Gustafsson NMS,Färnegårdh K,Bonagas N,Ninou AH,Groth P,Wiita E,Jönsson M,Hallberg K,Lehto J,Pennisi R,Martinsson J,Norström C,Hollers J,Schultz J,Andersson M,Markova N,Marttila P,Kim B,Norin M,Olin T,Helleday T
Mon Sep 24 00:00:00 UTC 2018
Targeting PFKFB3 radiosensitizes cancer cells and suppresses homologous recombination.
Nature communications
Gustafsson NMS,Färnegårdh K,Bonagas N,Ninou AH,Groth P,Wiita E,Jönsson M,Hallberg K,Lehto J,Pennisi R,Martinsson J,Norström C,Hollers J,Schultz J,Andersson M,Markova N,Marttila P,Kim B,Norin M,Olin T,Helleday T
Mon Sep 24 00:00:00 UTC 2018
FGF-dependent metabolic control of vascular development.
Nature
Yu P,Wilhelm K,Dubrac A,Tung JK,Alves TC,Fang JS,Xie Y,Zhu J,Chen Z,De Smet F,Zhang J,Jin SW,Sun L,Sun H,Kibbey RG,Hirschi KK,Hay N,Carmeliet P,Chittenden TW,Eichmann A,Potente M,Simons M
Thu May 11 00:00:00 UTC 2017
FGF-dependent metabolic control of vascular development.
Nature
Yu P,Wilhelm K,Dubrac A,Tung JK,Alves TC,Fang JS,Xie Y,Zhu J,Chen Z,De Smet F,Zhang J,Jin SW,Sun L,Sun H,Kibbey RG,Hirschi KK,Hay N,Carmeliet P,Chittenden TW,Eichmann A,Potente M,Simons M
Thu May 11 00:00:00 UTC 2017
Exercise-Induced Changes in Glucose Metabolism Promote Physiological Cardiac Growth.
Circulation
Gibb AA,Epstein PN,Uchida S,Zheng Y,McNally LA,Obal D,Katragadda K,Trainor P,Conklin DJ,Brittian KR,Tseng MT,Wang J,Jones SP,Bhatnagar A,Hill BG
Tue Nov 28 00:00:00 UTC 2017
Exercise-Induced Changes in Glucose Metabolism Promote Physiological Cardiac Growth.
Circulation
Gibb AA,Epstein PN,Uchida S,Zheng Y,McNally LA,Obal D,Katragadda K,Trainor P,Conklin DJ,Brittian KR,Tseng MT,Wang J,Jones SP,Bhatnagar A,Hill BG
Tue Nov 28 00:00:00 UTC 2017
6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase-3 is required for transforming growth factor β1-enhanced invasion of Panc1 cells in vitro.
Biochemical and biophysical research communications
Yalcin A,Solakoglu TH,Ozcan SC,Guzel S,Peker S,Celikler S,Balaban BD,Sevinc E,Gurpinar Y,Chesney JA
Sat Mar 11 00:00:00 UTC 2017
6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase-3 is required for transforming growth factor β1-enhanced invasion of Panc1 cells in vitro.
Biochemical and biophysical research communications
Yalcin A,Solakoglu TH,Ozcan SC,Guzel S,Peker S,Celikler S,Balaban BD,Sevinc E,Gurpinar Y,Chesney JA
Sat Mar 11 00:00:00 UTC 2017
PFKFB3, a Direct Target of p63, Is Required for Proliferation and Inhibits Differentiation in Epidermal Keratinocytes.
The Journal of investigative dermatology
Hamanaka RB,Mutlu GM
Thu Jun 01 00:00:00 UTC 2017
USP9X regulates centrosome duplication and promotes breast carcinogenesis.
Nature communications
Li X,Song N,Liu L,Liu X,Ding X,Song X,Yang S,Shan L,Zhou X,Su D,Wang Y,Zhang Q,Cao C,Ma S,Yu N,Yang F,Wang Y,Yao Z,Shang Y,Shi L
Fri Mar 31 00:00:00 UTC 2017
USP9X regulates centrosome duplication and promotes breast carcinogenesis.
Nature communications
Li X,Song N,Liu L,Liu X,Ding X,Song X,Yang S,Shan L,Zhou X,Su D,Wang Y,Zhang Q,Cao C,Ma S,Yu N,Yang F,Wang Y,Yao Z,Shang Y,Shi L
Fri Mar 31 00:00:00 UTC 2017
USP9X regulates centrosome duplication and promotes breast carcinogenesis.
Nature communications
Li X,Song N,Liu L,Liu X,Ding X,Song X,Yang S,Shan L,Zhou X,Su D,Wang Y,Zhang Q,Cao C,Ma S,Yu N,Yang F,Wang Y,Yao Z,Shang Y,Shi L
Fri Mar 31 00:00:00 UTC 2017
USP9X regulates centrosome duplication and promotes breast carcinogenesis.
Nature communications
Li X,Song N,Liu L,Liu X,Ding X,Song X,Yang S,Shan L,Zhou X,Su D,Wang Y,Zhang Q,Cao C,Ma S,Yu N,Yang F,Wang Y,Yao Z,Shang Y,Shi L
Fri Mar 31 00:00:00 UTC 2017
Endothelial adenosine A2a receptor-mediated glycolysis is essential for pathological retinal angiogenesis.
Nature communications
Liu Z,Yan S,Wang J,Xu Y,Wang Y,Zhang S,Xu X,Yang Q,Zeng X,Zhou Y,Gu X,Lu S,Fu Z,Fulton DJ,Weintraub NL,Caldwell RB,Zhang W,Wu C,Liu XL,Chen JF,Ahmad A,Kaddour-Djebbar I,Al-Shabrawey M,Li Q,Jiang X,Sun Y,Sodhi A,Smith L,Hong M,Huo Y
Tue Sep 19 00:00:00 UTC 2017
Endothelial adenosine A2a receptor-mediated glycolysis is essential for pathological retinal angiogenesis.
Nature communications
Liu Z,Yan S,Wang J,Xu Y,Wang Y,Zhang S,Xu X,Yang Q,Zeng X,Zhou Y,Gu X,Lu S,Fu Z,Fulton DJ,Weintraub NL,Caldwell RB,Zhang W,Wu C,Liu XL,Chen JF,Ahmad A,Kaddour-Djebbar I,Al-Shabrawey M,Li Q,Jiang X,Sun Y,Sodhi A,Smith L,Hong M,Huo Y
Tue Sep 19 00:00:00 UTC 2017
Ginkgetin induces cell death in breast cancer cells via downregulation of the estrogen receptor.
Oncology letters
Park Y,Woo SH,Seo SK,Kim H,Noh WC,Lee JK,Kwon BM,Min KN,Choe TB,Park IC
Sun Oct 01 00:00:00 UTC 2017
PFKFB3-Driven Macrophage Glycolytic Metabolism Is a Crucial Component of Innate Antiviral Defense.
Journal of immunology (Baltimore, Md. : 1950)
Jiang H,Shi H,Sun M,Wang Y,Meng Q,Guo P,Cao Y,Chen J,Gao X,Li E,Liu J
Sat Oct 01 00:00:00 UTC 2016
PFKFB3-Driven Macrophage Glycolytic Metabolism Is a Crucial Component of Innate Antiviral Defense.
Journal of immunology (Baltimore, Md. : 1950)
Jiang H,Shi H,Sun M,Wang Y,Meng Q,Guo P,Cao Y,Chen J,Gao X,Li E,Liu J
Sat Oct 01 00:00:00 UTC 2016
Inhibition of 6-phosphofructo-2-kinase (PFKFB3) suppresses glucose metabolism and the growth of HER2+ breast cancer.
Breast cancer research and treatment
O'Neal J,Clem A,Reynolds L,Dougherty S,Imbert-Fernandez Y,Telang S,Chesney J,Clem BF
Tue Nov 01 00:00:00 UTC 2016
Inhibition of 6-phosphofructo-2-kinase (PFKFB3) suppresses glucose metabolism and the growth of HER2+ breast cancer.
Breast cancer research and treatment
O'Neal J,Clem A,Reynolds L,Dougherty S,Imbert-Fernandez Y,Telang S,Chesney J,Clem BF
Tue Nov 01 00:00:00 UTC 2016
Inhibition of 6-phosphofructo-2-kinase (PFKFB3) suppresses glucose metabolism and the growth of HER2+ breast cancer.
Breast cancer research and treatment
O'Neal J,Clem A,Reynolds L,Dougherty S,Imbert-Fernandez Y,Telang S,Chesney J,Clem BF
Tue Nov 01 00:00:00 UTC 2016
Inhibition of 6-phosphofructo-2-kinase (PFKFB3) suppresses glucose metabolism and the growth of HER2+ breast cancer.
Breast cancer research and treatment
O'Neal J,Clem A,Reynolds L,Dougherty S,Imbert-Fernandez Y,Telang S,Chesney J,Clem BF
Tue Nov 01 00:00:00 UTC 2016
p53 coordinates DNA repair with nucleotide synthesis by suppressing PFKFB3 expression and promoting the pentose phosphate pathway.
Scientific reports
Franklin DA,He Y,Leslie PL,Tikunov AP,Fenger N,Macdonald JM,Zhang Y
Wed Nov 30 00:00:00 UTC 2016
p53 coordinates DNA repair with nucleotide synthesis by suppressing PFKFB3 expression and promoting the pentose phosphate pathway.
Scientific reports
Franklin DA,He Y,Leslie PL,Tikunov AP,Fenger N,Macdonald JM,Zhang Y
Wed Nov 30 00:00:00 UTC 2016
Glucose and Palmitate Differentially Regulate PFKFB3/iPFK2 and Inflammatory Responses in Mouse Intestinal Epithelial Cells.
Scientific reports
Botchlett R,Li H,Guo X,Qi T,Zhao J,Zheng J,Woo SL,Pei Y,Liu M,Hu X,Chen G,Guo T,Yang S,Li Q,Xiao X,Huo Y,Wu C
Fri Jul 08 00:00:00 UTC 2016
Glucose and Palmitate Differentially Regulate PFKFB3/iPFK2 and Inflammatory Responses in Mouse Intestinal Epithelial Cells.
Scientific reports
Botchlett R,Li H,Guo X,Qi T,Zhao J,Zheng J,Woo SL,Pei Y,Liu M,Hu X,Chen G,Guo T,Yang S,Li Q,Xiao X,Huo Y,Wu C
Fri Jul 08 00:00:00 UTC 2016
IKKβ promotes metabolic adaptation to glutamine deprivation via phosphorylation and inhibition of PFKFB3.
Genes & development
Reid MA,Lowman XH,Pan M,Tran TQ,Warmoes MO,Ishak Gabra MB,Yang Y,Locasale JW,Kong M
Mon Aug 15 00:00:00 UTC 2016
Type 2 Diabetes Dysregulates Glucose Metabolism in Cardiac Progenitor Cells.
The Journal of biological chemistry
Salabei JK,Lorkiewicz PK,Mehra P,Gibb AA,Haberzettl P,Hong KU,Wei X,Zhang X,Li Q,Wysoczynski M,Bolli R,Bhatnagar A,Hill BG
Fri Jun 24 00:00:00 UTC 2016
Type 2 Diabetes Dysregulates Glucose Metabolism in Cardiac Progenitor Cells.
The Journal of biological chemistry
Salabei JK,Lorkiewicz PK,Mehra P,Gibb AA,Haberzettl P,Hong KU,Wei X,Zhang X,Li Q,Wysoczynski M,Bolli R,Bhatnagar A,Hill BG
Fri Jun 24 00:00:00 UTC 2016
PFKFB3 Control of Cancer Growth by Responding to Circadian Clock Outputs.
Scientific reports
Chen L,Zhao J,Tang Q,Li H,Zhang C,Yu R,Zhao Y,Huo Y,Wu C
Fri Apr 15 00:00:00 UTC 2016
Glycolytic Reprogramming in Myofibroblast Differentiation and Lung Fibrosis.
American journal of respiratory and critical care medicine
Xie N,Tan Z,Banerjee S,Cui H,Ge J,Liu RM,Bernard K,Thannickal VJ,Liu G
Tue Dec 15 00:00:00 UTC 2015
Glycolytic Reprogramming in Myofibroblast Differentiation and Lung Fibrosis.
American journal of respiratory and critical care medicine
Xie N,Tan Z,Banerjee S,Cui H,Ge J,Liu RM,Bernard K,Thannickal VJ,Liu G
Tue Dec 15 00:00:00 UTC 2015
Glycolytic Reprogramming in Myofibroblast Differentiation and Lung Fibrosis.
American journal of respiratory and critical care medicine
Xie N,Tan Z,Banerjee S,Cui H,Ge J,Liu RM,Bernard K,Thannickal VJ,Liu G
Tue Dec 15 00:00:00 UTC 2015
Glycolytic Reprogramming in Myofibroblast Differentiation and Lung Fibrosis.
American journal of respiratory and critical care medicine
Xie N,Tan Z,Banerjee S,Cui H,Ge J,Liu RM,Bernard K,Thannickal VJ,Liu G
Tue Dec 15 00:00:00 UTC 2015
Metabolic control of the cell cycle.
Cell cycle (Georgetown, Tex.)
Kalucka J,Missiaen R,Georgiadou M,Schoors S,Lange C,De Bock K,Dewerchin M,Carmeliet P
Mon Aug 29 00:00:00 UTC 2016
Metabolic control of the cell cycle.
Cell cycle (Georgetown, Tex.)
Kalucka J,Missiaen R,Georgiadou M,Schoors S,Lange C,De Bock K,Dewerchin M,Carmeliet P
Mon Aug 29 00:00:00 UTC 2016
miR-26b inhibits proliferation, migration, invasion and apoptosis induction via the downregulation of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 driven glycolysis in osteosarcoma cells.
Oncology reports
Du JY,Wang LF,Wang Q,Yu LD
Wed Apr 01 00:00:00 UTC 2015
miR-26b inhibits proliferation, migration, invasion and apoptosis induction via the downregulation of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 driven glycolysis in osteosarcoma cells.
Oncology reports
Du JY,Wang LF,Wang Q,Yu LD
Wed Apr 01 00:00:00 UTC 2015
The monocarboxylate transporter 4 is required for glycolytic reprogramming and inflammatory response in macrophages.
The Journal of biological chemistry
Tan Z,Xie N,Banerjee S,Cui H,Fu M,Thannickal VJ,Liu G
Fri Jan 02 00:00:00 UTC 2015
The monocarboxylate transporter 4 is required for glycolytic reprogramming and inflammatory response in macrophages.
The Journal of biological chemistry
Tan Z,Xie N,Banerjee S,Cui H,Fu M,Thannickal VJ,Liu G
Fri Jan 02 00:00:00 UTC 2015
Endothelial PFKFB3 plays a critical role in angiogenesis.
Arteriosclerosis, thrombosis, and vascular biology
Xu Y,An X,Guo X,Habtetsion TG,Wang Y,Xu X,Kandala S,Li Q,Li H,Zhang C,Caldwell RB,Fulton DJ,Su Y,Hoda MN,Zhou G,Wu C,Huo Y
Sun Jun 01 00:00:00 UTC 2014
Endothelial PFKFB3 plays a critical role in angiogenesis.
Arteriosclerosis, thrombosis, and vascular biology
Xu Y,An X,Guo X,Habtetsion TG,Wang Y,Xu X,Kandala S,Li Q,Li H,Zhang C,Caldwell RB,Fulton DJ,Su Y,Hoda MN,Zhou G,Wu C,Huo Y
Sun Jun 01 00:00:00 UTC 2014
Inhibition of 6-phosphofructo-2-kinase (PFKFB3) induces autophagy as a survival mechanism.
Cancer & metabolism
Klarer AC,O'Neal J,Imbert-Fernandez Y,Clem A,Ellis SR,Clark J,Clem B,Chesney J,Telang S
Thu Jan 23 00:00:00 UTC 2014
Inhibition of 6-phosphofructo-2-kinase (PFKFB3) induces autophagy as a survival mechanism.
Cancer & metabolism
Klarer AC,O'Neal J,Imbert-Fernandez Y,Clem A,Ellis SR,Clark J,Clem B,Chesney J,Telang S
Thu Jan 23 00:00:00 UTC 2014
Estradiol stimulates glucose metabolism via 6-phosphofructo-2-kinase (PFKFB3).
The Journal of biological chemistry
Imbert-Fernandez Y,Clem BF,O'Neal J,Kerr DA,Spaulding R,Lanceta L,Clem AL,Telang S,Chesney J
Fri Mar 28 00:00:00 UTC 2014
Estradiol stimulates glucose metabolism via 6-phosphofructo-2-kinase (PFKFB3).
The Journal of biological chemistry
Imbert-Fernandez Y,Clem BF,O'Neal J,Kerr DA,Spaulding R,Lanceta L,Clem AL,Telang S,Chesney J
Fri Mar 28 00:00:00 UTC 2014
Estradiol stimulates glucose metabolism via 6-phosphofructo-2-kinase (PFKFB3).
The Journal of biological chemistry
Imbert-Fernandez Y,Clem BF,O'Neal J,Kerr DA,Spaulding R,Lanceta L,Clem AL,Telang S,Chesney J
Fri Mar 28 00:00:00 UTC 2014
Estradiol stimulates glucose metabolism via 6-phosphofructo-2-kinase (PFKFB3).
The Journal of biological chemistry
Imbert-Fernandez Y,Clem BF,O'Neal J,Kerr DA,Spaulding R,Lanceta L,Clem AL,Telang S,Chesney J
Fri Mar 28 00:00:00 UTC 2014
6-Phosphofructo-2-kinase (PFKFB3) promotes cell cycle progression and suppresses apoptosis via Cdk1-mediated phosphorylation of p27.
Cell death & disease
Yalcin A,Clem BF,Imbert-Fernandez Y,Ozcan SC,Peker S,O'Neal J,Klarer AC,Clem AL,Telang S,Chesney J
Thu Jul 17 00:00:00 UTC 2014
6-Phosphofructo-2-kinase (PFKFB3) promotes cell cycle progression and suppresses apoptosis via Cdk1-mediated phosphorylation of p27.
Cell death & disease
Yalcin A,Clem BF,Imbert-Fernandez Y,Ozcan SC,Peker S,O'Neal J,Klarer AC,Clem AL,Telang S,Chesney J
Thu Jul 17 00:00:00 UTC 2014
Role of PFKFB3-driven glycolysis in vessel sprouting.
Cell
De Bock K,Georgiadou M,Schoors S,Kuchnio A,Wong BW,Cantelmo AR,Quaegebeur A,Ghesquière B,Cauwenberghs S,Eelen G,Phng LK,Betz I,Tembuyser B,Brepoels K,Welti J,Geudens I,Segura I,Cruys B,Bifari F,Decimo I,Blanco R,Wyns S,Vangindertael J,Rocha S,Collins RT,Munck S,Daelemans D,Imamura H,Devlieger R,Rider M,Van Veldhoven PP,Schuit F,Bartrons R,Hofkens J,Fraisl P,Telang S,Deberardinis RJ,Schoonjans L,Vinckier S,Chesney J,Gerhardt H,Dewerchin M,Carmeliet P
Thu Aug 01 00:00:00 UTC 2013
Role of PFKFB3-driven glycolysis in vessel sprouting.
Cell
De Bock K,Georgiadou M,Schoors S,Kuchnio A,Wong BW,Cantelmo AR,Quaegebeur A,Ghesquière B,Cauwenberghs S,Eelen G,Phng LK,Betz I,Tembuyser B,Brepoels K,Welti J,Geudens I,Segura I,Cruys B,Bifari F,Decimo I,Blanco R,Wyns S,Vangindertael J,Rocha S,Collins RT,Munck S,Daelemans D,Imamura H,Devlieger R,Rider M,Van Veldhoven PP,Schuit F,Bartrons R,Hofkens J,Fraisl P,Telang S,Deberardinis RJ,Schoonjans L,Vinckier S,Chesney J,Gerhardt H,Dewerchin M,Carmeliet P
Thu Aug 01 00:00:00 UTC 2013
Small molecule inhibition of 6-phosphofructo-2-kinase suppresses t cell activation.
Journal of translational medicine
Telang S,Clem BF,Klarer AC,Clem AL,Trent JO,Bucala R,Chesney J
Wed May 16 00:00:00 UTC 2012
Small molecule inhibition of 6-phosphofructo-2-kinase suppresses t cell activation.
Journal of translational medicine
Telang S,Clem BF,Klarer AC,Clem AL,Trent JO,Bucala R,Chesney J
Wed May 16 00:00:00 UTC 2012
