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Invitrogen
PFKP Recombinant Rabbit Monoclonal Antibody (5B7E3)
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FIGURE: 1 / 5
PFKP Antibody (MA5-51364) in IHC (P)
Immunohistochemistry analysis of PFKP in paraffin-embedded human liver cancer. Samples were incubated with PFKP Recombinant monoclonal antibody (Product # MA5-51364) using a dilution of 1:50 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
Product Details
MA5-51364
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
5B7E3
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 336-540 of human PFKP (NP_002618.1).
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_3094266
Product Specific Information
Immunogen sequence: ATPDTPACVV SLNGNHAVRL PLMECVQMTQ DVQKAMDERR FQDAVRLRGR SFAGNLNTYK RLAIKLPDDQ IPKTNCNVAV INVGAPAAGM NAAVRSAVRV GIADGHRMLA IYDGFDGFAK GQIKEIGWTD VGGWTGQGGS ILGTKRVLPG KYLEEIATQM RTHSINALLI IGGFEAYLGL LELSAAREKH EEFCVPMVMV PATVS
Target Information
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The AGC kinase group consists of 63 kinases including the cyclic nucleotide-regulated protein kinase (PKA & PKG) family, the diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family, the related to PKA and PKC (RAC/Akt) protein kinase family, the kinases that phosphorylate G protein-coupled receptors family (ARK), and the kinases that phosphorylate ribosomal protein S6 family (RSK).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 6-phosphofructo-1-kinase, C-type; 6-phosphofructokinase type C; 6-phosphofructokinase, platelet type; ATP-dependent 6-phosphofructokinase, platelet type; ATP-dependent 6-phosphofructokinase, platelet type {ECO:0000255|HAMAP-Rule:MF_03184}; ATP-PFK; ATP-PFK {ECO:0000255|HAMAP-Rule:MF_03184}; ATP:D-fructose 6-phosphate 1-phosphotransferase; EC 2.7.1.11; K6PP; PFK 1; PFK-C; PFK1; Phosphofructo-1-kinase isozyme C; Phosphofructokinase; phosphofructokinase 1; Phosphofructokinase, platelet type; Phosphohexokinase; phosphohexokinase {ECO:0000255|HAMAP-Rule:MF_03184}
Gene Aliases: 1200015H23Rik; 9330125N24Rik; ATP-PFK; PFK-C; PFK-P; Pfkc; PFKF; PFKP
UniProt ID: (Human) Q01813, (Rat) P47860, (Mouse) Q9WUA3
Entrez Gene ID: (Human) 5214, (Rat) 60416, (Mouse) 56421
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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