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Product Details
H00005217-M04
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
5F11
Immunogen
PFN2 (NP_002619, 41 a.a. approximately 140 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: QSITPIEIDM IVGKDREGFF TNGLTLGAKK CSVIRDSLYV DGDCTMDIRT KSQGGEPTYN VAVGRAGRAL VIVMGKEGVH GGTLNKKAYE LALYLRRSDV
Target Information
Profilin 2 is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Profilin II; Profilin-2
Gene Aliases: D3S1319E; PFL; PFN2
UniProt ID: (Human) P35080
Entrez Gene ID: (Human) 5217
negative regulation of epithelial cell migration
actin cytoskeleton organization
negative regulation of actin filament polymerization
positive regulation of actin filament polymerization
positive regulation of actin filament bundle assembly
positive regulation of ATPase activity
positive regulation of peptidyl-serine phosphorylation
protein stabilization
positive regulation of stress fiber assembly
negative regulation of ruffle assembly
regulation of synaptic vesicle exocytosis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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