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Proteintech
PHACTR4 Polyclonal Antibody
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Product Details
13408-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PHACTR4 Fusion Protein Ag4054 (403-702 aa encoded by BC029266)
Conjugate
Form
Liquid
Concentration
0.34 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: FGEPHIPSR LPPLPLHIRI QQALTSPLPM TPILEGSHRA HSLLFENSDS FSEDSSTLGR TRSLPITIEM LKVPDDEEEE EQTCPSTFSE EMTPTSVIPK LPQCLREEEE KESDSDSEGP IQYRDEEDED ESYQSALANK VKRKDTLAMK LNHRPSEPEL NLNSWPCKSK EEWNEIRHQI GNTLIRRLSQ RPTPEELEQR NILQPKNEAD RQAEKREIKR RLTRKLSQRP TVAELLARKI LRFNEYVEVT DAQDYDRRAD KPWTKLTPAD KAAIRKELNE FKSSEMEVHE ESKHFTRYHR P (403-702 aa encoded by BC029266)
Target Information
This gene encodes a member of the phosphatase and actin regulator (PHACTR) family. Other PHACTR family members have been shown to inhibit protein phosphatase 1 (PP1) activity, and the homolog of this gene in the mouse has been shown to interact with actin and PP1. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Humdy; Phosphatase and actin regulator 4; Protein Humpty dumpty; protein phosphatase 1, regulatory subunit 124
Gene Aliases: 3110001B12Rik; AI527228; AW495572; C330013F19Rik; Kiaa4120; mKIAA4120; N28169; PHACTR4; PPP1R124; PRO2963
UniProt ID: (Human) Q8IZ21, (Mouse) Q501J7
Entrez Gene ID: (Human) 65979, (Mouse) 100169, (Rat) 682920
neural crest cell migration
neural tube closure
Rho protein signal transduction
actin cytoskeleton organization
positive regulation of catalytic activity
enteric nervous system development
regulation of cell cycle
closure of optic fissure
negative regulation of integrin-mediated signaling pathway
multicellular organism development
nervous system development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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