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Immunogen sequence: GGAVNMCYRT LYIGTGADMD VCLTNYGHCN YVSGKHACIF YDENTKHYEL LNYSEHGTTV DNVLYSCDFS EKTPPTPPSS IVAKVQ
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
Acts as a transcriptional repressor. Involved in recruitment of functional SIN3A complexes to DNA. Represses transcription at least in part through the activity of an associated histone deacetylase (HDAC). May also repress transcription in a SIN3A-independent manner through recruitment of functional TLE5 complexes to DNA. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Pf1; PHD factor 1; PHD finger protein 12; PHD zinc finger transcription factor; PHF12; PHF12 (HGNC:20816)
Gene Aliases: KIAA1523; PF1; PHF12
UniProt ID: (Human) Q96QT6
Entrez Gene ID: (Human) 57649
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