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PHF14 Polyclonal Antibody

PHF14 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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PHF14 Antibody (24787-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human kidney tissue slide using 24787-1-AP ( PHF14 Antibody) at dilution of 1:50 (under 40x lens).

PHF14 Antibody in Immunoprecipitation (IP)

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Product Details

24787-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 5 publications 5 publications

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

View 1 publication 1 publication

ChIP assay (ChIP)

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

PHF14 Fusion Protein Ag20542 (536-885 aa encoded by BC152414)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.43 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: RINARLQQY RAKAELARST RPQAWVPREK LPRPLTSSAS AIRKLMRKAE LMGISTDIFP VDNSDTSSSV DGRRKHKQPA LTADFVNYYF ERNMRMIQIQ ENMAEQKNIK DKLENEQEKL HVEYNKLCES LEELQNLNGK LRSEGQGIWA LLGRITGQKL NIPAILRAPK ERKPSKKEGG TQKTSTLPAV LYSCGICKKN HDQHLLLLCD TCKLHYHLGC LDPPLTRMPR KTKNSYWQCS ECDQAGSSDM EADMAMETLP DGTKRSRRQI KEPVKFVPQD VPPEPKKIPI RNTRTRGRKR SFVPEEEKHE ERVPRERRQR QSVLQKKPKA EDLRTECATC KGTGDNENLV R (536-885 aa encoded by BC152414)

Target Information

PHF14 gene ontology annotations related to this gene include metal ion binding.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

PHF14 enhances DNA methylation of SMAD7 gene to promote TGF-β-driven lung adenocarcinoma metastasis.

Cell discovery

Tian H,Liu C,Yu J,Han J,Du J,Liang S,Wang W,Liu Q,Lian R,Zhu T,Wu S,Tao T,Ye Y,Zhao J,Yang Y,Zhu X,Cai J,Wu J,Li M

Tue Apr 18 00:00:00 UTC 2023

PHF14 enhances DNA methylation of SMAD7 gene to promote TGF-β-driven lung adenocarcinoma metastasis.

Cell discovery

Tian H,Liu C,Yu J,Han J,Du J,Liang S,Wang W,Liu Q,Lian R,Zhu T,Wu S,Tao T,Ye Y,Zhao J,Yang Y,Zhu X,Cai J,Wu J,Li M

Tue Apr 18 00:00:00 UTC 2023

PHF14 enhances DNA methylation of SMAD7 gene to promote TGF-β-driven lung adenocarcinoma metastasis.

Cell discovery

Tian H,Liu C,Yu J,Han J,Du J,Liang S,Wang W,Liu Q,Lian R,Zhu T,Wu S,Tao T,Ye Y,Zhao J,Yang Y,Zhu X,Cai J,Wu J,Li M

Tue Apr 18 00:00:00 UTC 2023

PHF14 enhances DNA methylation of SMAD7 gene to promote TGF-β-driven lung adenocarcinoma metastasis.

Cell discovery

Tian H,Liu C,Yu J,Han J,Du J,Liang S,Wang W,Liu Q,Lian R,Zhu T,Wu S,Tao T,Ye Y,Zhao J,Yang Y,Zhu X,Cai J,Wu J,Li M

Tue Apr 18 00:00:00 UTC 2023

The high mobility group protein HMG20A cooperates with the histone reader PHF14 to modulate TGFβ and Hippo pathways.

Nucleic acids research

Gómez-Marín E,Posavec-Marjanović M,Zarzuela L,Basurto-Cayuela L,Guerrero-Martínez JA,Arribas G,Yerbes R,Ceballos-Chávez M,Rodríguez-Paredes M,Tomé M,Durán RV,Buschbeck M,Reyes JC

Fri Sep 23 00:00:00 UTC 2022

The high mobility group protein HMG20A cooperates with the histone reader PHF14 to modulate TGFβ and Hippo pathways.

Nucleic acids research

Gómez-Marín E,Posavec-Marjanović M,Zarzuela L,Basurto-Cayuela L,Guerrero-Martínez JA,Arribas G,Yerbes R,Ceballos-Chávez M,Rodríguez-Paredes M,Tomé M,Durán RV,Buschbeck M,Reyes JC

Fri Sep 23 00:00:00 UTC 2022

The high mobility group protein HMG20A cooperates with the histone reader PHF14 to modulate TGFβ and Hippo pathways.

Nucleic acids research

Gómez-Marín E,Posavec-Marjanović M,Zarzuela L,Basurto-Cayuela L,Guerrero-Martínez JA,Arribas G,Yerbes R,Ceballos-Chávez M,Rodríguez-Paredes M,Tomé M,Durán RV,Buschbeck M,Reyes JC

Fri Sep 23 00:00:00 UTC 2022

PHF14 Promotes Cell Proliferation and Migration through the AKT and ERK1/2 Pathways in Gastric Cancer Cells.

BioMed research international

Zhao Y,He J,Li Y,Xu M,Peng X,Mao J,Xu B,Cui H

Mon Mar 22 00:00:00 UTC 2021

PHF14 Promotes Cell Proliferation and Migration through the AKT and ERK1/2 Pathways in Gastric Cancer Cells.

BioMed research international

Zhao Y,He J,Li Y,Xu M,Peng X,Mao J,Xu B,Cui H

Mon Mar 22 00:00:00 UTC 2021

Integrated analysis of H2A.Z isoforms function reveals a complex interplay in gene regulation.

eLife

Lamaa A,Humbert J,Aguirrebengoa M,Cheng X,Nicolas E,Côté J,Trouche D

Fri Feb 28 00:00:00 UTC 2020

Pulsed SILAC-based proteomic analysis unveils hypoxia- and serum starvation-induced de novo protein synthesis with PHD finger protein 14 (PHF14) as a hypoxia sensitive epigenetic regulator in cell cycle progression.

Oncotarget

Park JE,Tse SW,Xue G,Assisi C,Maqueda AS,Ramon GPX,Low JK,Kon OL,Tay CY,Tam JP,Sze SK

Fri Mar 15 00:00:00 UTC 2019

Bioinformatics

Protein Aliases: PHD finger protein 14

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Gene Aliases: KIAA0783; PHF14

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UniProt ID: (Human) O94880

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Entrez Gene ID: (Human) 9678

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Function(s)

zinc ion binding

Process(es)

negative regulation of transcription from RNA polymerase II promoter lung alveolus development negative regulation of platelet-derived growth factor receptor-alpha signaling pathway negative regulation of mesenchymal cell proliferation involved in lung development

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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PHF14 Polyclonal Antibody

PHF14 Antibody (24787-1-AP) in IHC (P)

Product Details

24787-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

ChIP assay (ChIP)

Species Reactivity

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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