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Product Details
H00023338-B02P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PHF15 (AAH04292.1, 1 a.a. approximately 246 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MAMSEWPLNN GHREDPAPGL LSEELLQDEE TLLSFMRDPS LRPGDPARKA RGRTRLPAKK KPPPPPPQDG PGSRTTPDKA PKKTWGQDAG SGKGGQGPPT RKPPRRTSSH LPSSPAAGDC PILATPESPP PLAPETPDEA ASVAADSDVQ VPGPAASPKP LGRLRPPRES KVTRRLPGAR PDAGMGPPSA VAERPKISLH FDTETDGYFS DGEMSDSDVE AEDGGVQRGP REAGAEEVVR MGVLAS
Target Information
Scaffold subunit of some HBO1 complexes, which have a histone H4 acetyltransferase activity (PubMed:16387653). Acts as a E3 ubiquitin-protein ligase mediating the ubiquitination and subsequent proteasomal degradation of target protein histone demethylase KDM1A (PubMed:25018020). Also acts as a ubiquitin ligase E3 toward itself. Positive regulator of neurogenesis. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: E3 ubiquitin-protein ligase Jade-2; Jade family PHD finger protein 2; PHD finger protein 15
Gene Aliases: JADE-2; JADE2; KIAA0239; PHF15
UniProt ID: (Human) Q9NQC1
Entrez Gene ID: (Human) 23338
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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