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          • Primary Antibodies ›
          • PHF21A Antibodies

          Invitrogen

          PHF21A Polyclonal Antibody

          View all (10) PHF21A antibodies
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          Cite PHF21A Polyclonal Antibody

          • Antibody Testing Data (1)
          PHF21A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          PHF21A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          FIGURE: 1 / 1

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          PHF21A Antibody (PA5-54829) in IHC (P)

          Immunohistochemical analysis of PHF21A in human smooth muscle using PHF21A Polyclonal Antibody (Product # PA5-54829) shows strong cytoplasmic positivity in smooth muscle cells. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          PHF21A Antibody in Immunohistochemistry (Paraffin) (IHC (P))

          Product Details

          PA5-54829

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200-1:500
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human PHF21A. Recombinant protein control fragment (Product #RP-93601).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.2 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2645491

          Product Specific Information

          Immunogen sequence: QEREQLEQKV KQLSNSISKC MEMKNTILAR QKEMHSSLEK VKQLIRLIHG IDLSKPVDSE ATVGAISNGP DCTPPANAAT STPAPSPSSQ SCTANCNQG

          Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 93%.

          Target Information

          PHF21A (PHD finger protein 21A) is a component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, PHF21A may act as a scaffold.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: BHC80a; BRAF35-HDAC complex protein BHC80; BRAF35/HDAC2 complex (80 kDa); PHD finger protein 21A

          View more View less

          Gene Aliases: BHC80; BM-006; KIAA1696; PHF21A

          View more View less

          UniProt ID: (Human) Q96BD5

          View more View less

          Entrez Gene ID: (Human) 51317

          View more View less

          Function(s)
          RNA polymerase II regulatory region sequence-specific DNA binding chromatin binding transcription cofactor activity histone deacetylase activity protein binding zinc ion binding histone binding
          Process(es)
          transcription, DNA-templated regulation of transcription, DNA-templated blood coagulation histone deacetylation
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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