Product References
The E592K variant of SF3B1 creates unique RNA missplicing and associates with high-risk MDS without ring sideroblasts.
Research square
Choi IY,Ling J,Zhang J,Helmenstine E,Walter W,Bergman R,Philippe C,Manley J,Rouault-Pierre K,Li B,Wiseman D,Ouseph M,Bernard E,Li X,Haferlach T,Fazal S,Jain T,Gocke C,DeZern A,Dalton WB
Fri Apr 14 00:00:00 UTC 2023
The phosphorylation of PHF5A by TrkA-ERK1/2-ABL1 cascade regulates centrosome separation.
Cell death & disease
Song C,Zhang Y,Li Y,Bie J,Wang Z,Yang X,Li H,Zhu L,Zhang T,Chang Q,Luo J
Thu Feb 09 00:00:00 UTC 2023
The phosphorylation of PHF5A by TrkA-ERK1/2-ABL1 cascade regulates centrosome separation.
Cell death & disease
Song C,Zhang Y,Li Y,Bie J,Wang Z,Yang X,Li H,Zhu L,Zhang T,Chang Q,Luo J
Thu Feb 09 00:00:00 UTC 2023
SIRT7-Induced PHF5A Decrotonylation Regulates Aging Progress Through Alternative Splicing-Mediated Downregulation of CDK2.
Frontiers in cell and developmental biology
Yu AQ,Wang J,Jiang ST,Yuan LQ,Ma HY,Hu YM,Han XM,Tan LM,Wang ZX
Tue Oct 05 00:00:00 UTC 2021
SIRT7-Induced PHF5A Decrotonylation Regulates Aging Progress Through Alternative Splicing-Mediated Downregulation of CDK2.
Frontiers in cell and developmental biology
Yu AQ,Wang J,Jiang ST,Yuan LQ,Ma HY,Hu YM,Han XM,Tan LM,Wang ZX
Tue Oct 05 00:00:00 UTC 2021
PHF5A promotes colorectal cancerprogression by alternative splicing of TEAD2.
Molecular therapy. Nucleic acids
Chang Y,Zhao Y,Wang L,Wu M,He C,Huang M,Lei Z,Yang J,Han S,Wang B,Chen Y,Liu C,Yu H,Xue L,Geng J,Chen Y,Dai T,Ren L,Wang Q,Liu X,Chu X,Chen C
Fri Dec 03 00:00:00 UTC 2021
Enterotoxigenic Bacteroidesfragilis Promotes Intestinal Inflammation and Malignancy by Inhibiting Exosome-Packaged miR-149-3p.
Gastroenterology
Cao Y,Wang Z,Yan Y,Ji L,He J,Xuan B,Shen C,Ma Y,Jiang S,Ma D,Tong T,Zhang X,Gao Z,Zhu X,Fang JY,Chen H,Hong J
Mon Nov 01 00:00:00 UTC 2021
RNA Polymerase II-Associated Factor 1 Regulates Stem Cell Features of Pancreatic Cancer Cells, Independently of the PAF1 Complex, via Interactions With PHF5A and DDX3.
Gastroenterology
Karmakar S,Rauth S,Nallasamy P,Perumal N,Nimmakayala RK,Leon F,Gupta R,Barkeer S,Venkata RC,Raman V,Rachagani S,Ponnusamy MP,Batra SK
Sun Nov 01 00:00:00 UTC 2020
RNA Polymerase II-Associated Factor 1 Regulates Stem Cell Features of Pancreatic Cancer Cells, Independently of the PAF1 Complex, via Interactions With PHF5A and DDX3.
Gastroenterology
Karmakar S,Rauth S,Nallasamy P,Perumal N,Nimmakayala RK,Leon F,Gupta R,Barkeer S,Venkata RC,Raman V,Rachagani S,Ponnusamy MP,Batra SK
Sun Nov 01 00:00:00 UTC 2020
RNA Polymerase II-Associated Factor 1 Regulates Stem Cell Features of Pancreatic Cancer Cells, Independently of the PAF1 Complex, via Interactions With PHF5A and DDX3.
Gastroenterology
Karmakar S,Rauth S,Nallasamy P,Perumal N,Nimmakayala RK,Leon F,Gupta R,Barkeer S,Venkata RC,Raman V,Rachagani S,Ponnusamy MP,Batra SK
Sun Nov 01 00:00:00 UTC 2020
RNA Polymerase II-Associated Factor 1 Regulates Stem Cell Features of Pancreatic Cancer Cells, Independently of the PAF1 Complex, via Interactions With PHF5A and DDX3.
Gastroenterology
Karmakar S,Rauth S,Nallasamy P,Perumal N,Nimmakayala RK,Leon F,Gupta R,Barkeer S,Venkata RC,Raman V,Rachagani S,Ponnusamy MP,Batra SK
Sun Nov 01 00:00:00 UTC 2020
Acetylation of PHF5A Modulates Stress Responses and Colorectal Carcinogenesis through Alternative Splicing-Mediated Upregulation of KDM3A.
Molecular cell
Wang Z,Yang X,Liu C,Li X,Zhang B,Wang B,Zhang Y,Song C,Zhang T,Liu M,Liu B,Ren M,Jiang H,Zou J,Liu X,Zhang H,Zhu WG,Yin Y,Zhang Z,Gu W,Luo J
Thu Jun 20 00:00:00 UTC 2019
PHF5A Epigenetically Inhibits Apoptosis to Promote Breast Cancer Progression.
Cancer research
Zheng YZ,Xue MZ,Shen HJ,Li XG,Ma D,Gong Y,Liu YR,Qiao F,Xie HY,Lian B,Sun WL,Zhao HY,Yao L,Zuo WJ,Li DQ,Wang P,Hu X,Shao ZM
Fri Jun 15 00:00:00 UTC 2018
PHF5A Epigenetically Inhibits Apoptosis to Promote Breast Cancer Progression.
Cancer research
Zheng YZ,Xue MZ,Shen HJ,Li XG,Ma D,Gong Y,Liu YR,Qiao F,Xie HY,Lian B,Sun WL,Zhao HY,Yao L,Zuo WJ,Li DQ,Wang P,Hu X,Shao ZM
Fri Jun 15 00:00:00 UTC 2018
PHF5A Epigenetically Inhibits Apoptosis to Promote Breast Cancer Progression.
Cancer research
Zheng YZ,Xue MZ,Shen HJ,Li XG,Ma D,Gong Y,Liu YR,Qiao F,Xie HY,Lian B,Sun WL,Zhao HY,Yao L,Zuo WJ,Li DQ,Wang P,Hu X,Shao ZM
Fri Jun 15 00:00:00 UTC 2018
PHF5A Epigenetically Inhibits Apoptosis to Promote Breast Cancer Progression.
Cancer research
Zheng YZ,Xue MZ,Shen HJ,Li XG,Ma D,Gong Y,Liu YR,Qiao F,Xie HY,Lian B,Sun WL,Zhao HY,Yao L,Zuo WJ,Li DQ,Wang P,Hu X,Shao ZM
Fri Jun 15 00:00:00 UTC 2018
PHF5A Epigenetically Inhibits Apoptosis to Promote Breast Cancer Progression.
Cancer research
Zheng YZ,Xue MZ,Shen HJ,Li XG,Ma D,Gong Y,Liu YR,Qiao F,Xie HY,Lian B,Sun WL,Zhao HY,Yao L,Zuo WJ,Li DQ,Wang P,Hu X,Shao ZM
Fri Jun 15 00:00:00 UTC 2018
PHF5A Epigenetically Inhibits Apoptosis to Promote Breast Cancer Progression.
Cancer research
Zheng YZ,Xue MZ,Shen HJ,Li XG,Ma D,Gong Y,Liu YR,Qiao F,Xie HY,Lian B,Sun WL,Zhao HY,Yao L,Zuo WJ,Li DQ,Wang P,Hu X,Shao ZM
Fri Jun 15 00:00:00 UTC 2018
The cryo-EM structure of the SF3b spliceosome complex bound to a splicing modulator reveals a pre-mRNA substrate competitive mechanism of action.
Genes & development
Finci LI,Zhang X,Huang X,Zhou Q,Tsai J,Teng T,Agrawal A,Chan B,Irwin S,Karr C,Cook A,Zhu P,Reynolds D,Smith PG,Fekkes P,Buonamici S,Larsen NA
Thu Feb 01 00:00:00 UTC 2018
The cryo-EM structure of the SF3b spliceosome complex bound to a splicing modulator reveals a pre-mRNA substrate competitive mechanism of action.
Genes & development
Finci LI,Zhang X,Huang X,Zhou Q,Tsai J,Teng T,Agrawal A,Chan B,Irwin S,Karr C,Cook A,Zhu P,Reynolds D,Smith PG,Fekkes P,Buonamici S,Larsen NA
Thu Feb 01 00:00:00 UTC 2018
PHD-finger domain protein 5A functions as a novel oncoprotein in lung adenocarcinoma.
Journal of experimental & clinical cancer research : CR
Yang Y,Zhu J,Zhang T,Liu J,Li Y,Zhu Y,Xu L,Wang R,Su F,Ou Y,Wu Q
Thu Mar 22 00:00:00 UTC 2018
PHD-finger domain protein 5A functions as a novel oncoprotein in lung adenocarcinoma.
Journal of experimental & clinical cancer research : CR
Yang Y,Zhu J,Zhang T,Liu J,Li Y,Zhu Y,Xu L,Wang R,Su F,Ou Y,Wu Q
Thu Mar 22 00:00:00 UTC 2018
PHD-finger domain protein 5A functions as a novel oncoprotein in lung adenocarcinoma.
Journal of experimental & clinical cancer research : CR
Yang Y,Zhu J,Zhang T,Liu J,Li Y,Zhu Y,Xu L,Wang R,Su F,Ou Y,Wu Q
Thu Mar 22 00:00:00 UTC 2018
PHD-finger domain protein 5A functions as a novel oncoprotein in lung adenocarcinoma.
Journal of experimental & clinical cancer research : CR
Yang Y,Zhu J,Zhang T,Liu J,Li Y,Zhu Y,Xu L,Wang R,Su F,Ou Y,Wu Q
Thu Mar 22 00:00:00 UTC 2018
Splicing modulators act at the branch point adenosine binding pocket defined by the PHF5A-SF3b complex.
Nature communications
Teng T,Tsai JH,Puyang X,Seiler M,Peng S,Prajapati S,Aird D,Buonamici S,Caleb B,Chan B,Corson L,Feala J,Fekkes P,Gerard B,Karr C,Korpal M,Liu X,T Lowe J,Mizui Y,Palacino J,Park E,Smith PG,Subramanian V,Wu ZJ,Zou J,Yu L,Chicas A,Warmuth M,Larsen N,Zhu P
Thu May 25 00:00:00 UTC 2017
Regulation of transcriptional elongation in pluripotency and cell differentiation by the PHD-finger protein Phf5a.
Nature cell biology
Strikoudis A,Lazaris C,Trimarchi T,Galvao Neto AL,Yang Y,Ntziachristos P,Rothbart S,Buckley S,Dolgalev I,Stadtfeld M,Strahl BD,Dynlacht BD,Tsirigos A,Aifantis I
Tue Nov 01 00:00:00 UTC 2016
Regulation of transcriptional elongation in pluripotency and cell differentiation by the PHD-finger protein Phf5a.
Nature cell biology
Strikoudis A,Lazaris C,Trimarchi T,Galvao Neto AL,Yang Y,Ntziachristos P,Rothbart S,Buckley S,Dolgalev I,Stadtfeld M,Strahl BD,Dynlacht BD,Tsirigos A,Aifantis I
Tue Nov 01 00:00:00 UTC 2016
