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PI4KB Polyclonal Antibody

FIGURE: 1 / 4

PI4KB Antibody (13247-1-AP) in WB

Jurkat cells were subjected to SDS PAGE followed by western blot with 13247-1-AP (PI4KB antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

PI4KB Antibody in Immunoprecipitation (IP)

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Product Details

13247-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 5 publications 5 publications

Immunocytochemistry (ICC/IF)

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

Not applicable (N/A)

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

PI4KB Fusion Protein Ag3989 (449-801 aa encoded by BC040300)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.13 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: IGELQVELP EVHTNSCDNI SQFSVDSITS QESKEPVFIA AGDIRRRLSE QLAHTPTAFK RDPEDPSAVA LKEPWQEKVR RIREGSPYGH LPNWRLLSVI VKCGDDLRQE LLAFQVLKQL QSIWEQERVP LWIKPYKILV ISADSGMIEP VVNAVSIHQV KKQSQLSLLD YFLQEHGSYT TEAFLSAQRN FVQSCAGYCL VCYLLQVKDR HNGNILLDAE GHIIHIDFGF ILSSSPRNLG FETSAFKLTT EFVDVMGGLD GDMFNYYKML MLQGLIAARK HMDKVVQIVE IMQQGSQLPC FHGSSTIRNL KERFHMSMTE EQLQLLVEQM VDGSMRSITT KLYDGFQYLT NGIM (449-801 aa encoded by B C040300)

Target Information

PI4KB and PI4KA are the two human type III PI4 kinases, which share sequence similarly with PI3 kinases and phosphorylate the 4 position of phosphotidyl inositol. Transporter for alanine, serine, cysteine, and threonine. Exhibits sodium dependence. Target protein phosphorylates phosphatidylinositol (PtdIns) at the D4 position of the inositol ring; may play a role in neuronal differentiation and maturation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Neonatal exposure to sevoflurane induces adolescent neurobehavioral dysfunction by interfering with hippocampal glycerophoslipid metabolism in rats.

Cerebral cortex (New York, N.Y. : 1991)

Wang Y,Li H,Zhao Y,Qin F,Wang L,Jiang L,Wang X,Chen R,He Y,Wei Q,Li S,Chen Y,Xiao Y,Dai Y,Bu Q,Zhao Y,Tian J,Wang H,Cen X

Mon Feb 20 00:00:00 UTC 2023

Construction of coxsackievirus B5 viruses with luciferase reporters and their applications in vitro and in vivo.

Virologica Sinica

Guo S,Xun M,Fan T,Li X,Yao H,Li X,Wu B,Yang H,Ma C,Wang H

Tue Aug 01 00:00:00 UTC 2023

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

The EMBO journal

Li FL,Wu Z,Gao YQ,Bowling FZ,Franklin JM,Hu C,Suhandynata RT,Frohman MA,Airola MV,Zhou H,Guan KL

Thu Sep 01 00:00:00 UTC 2022

Intercellular transfer of activated STING triggered by RAB22A-mediated non-canonical autophagy promotes antitumor immunity.

Cell research

Gao Y,Zheng X,Chang B,Lin Y,Huang X,Wang W,Ding S,Zhan W,Wang S,Xiao B,Huo L,Yu Y,Chen Y,Gong R,Wu Y,Zhang R,Zhong L,Wang X,Chen Q,Gao S,Jiang Z,Wei D,Kang T

Thu Dec 01 00:00:00 UTC 2022

Type II phosphatidylinositol 4-kinases function sequentially in cargo delivery from early endosomes to melanosomes.

The Journal of cell biology

Zhu Y,Li S,Jaume A,Jani RA,Delevoye C,Raposo G,Marks MS

Mon Nov 07 00:00:00 UTC 2022

Reverse Genetic Approaches for the Generation of Full Length and Subgenomic Replicon of EV71 Virus.

Frontiers in microbiology

Yang H,Zhao X,Xun M,Ma C,Wang H

Tue Jun 08 00:00:00 UTC 2021

Depletion of phosphatidylinositol 4-phosphate at the Golgi translocates K-Ras to mitochondria.

Journal of cell science

Miller TE,Henkels KM,Huddleston M,Salisbury R,Hussain SM,Sasaki AT,Cho KJ

Thu Aug 22 00:00:00 UTC 2019

Enterovirus 71 protease 2Apro and 3Cpro differentially inhibit the cellular endoplasmic reticulum-associated degradation (ERAD) pathway via distinct mechanisms, and enterovirus 71 hijacks ERAD component p97 to promote its replication.

PLoS pathogens

Wang T,Wang B,Huang H,Zhang C,Zhu Y,Pei B,Cheng C,Sun L,Wang J,Jin Q,Zhao Z

Sun Oct 01 00:00:00 UTC 2017

PLoS pathogens

Wang T,Wang B,Huang H,Zhang C,Zhu Y,Pei B,Cheng C,Sun L,Wang J,Jin Q,Zhao Z

Sun Oct 01 00:00:00 UTC 2017

Bioinformatics

Protein Aliases: catalytic phosphatidylinositol 4-kinase beta; NPIK; phosphatidylinositol 4-kinase; Phosphatidylinositol 4-kinase beta; phosphatidylinositol 4-kinase, catalytic, beta; phosphatidylinositol 4-kinase, catalytic, beta polypeptide; phosphatidylinositol 4-kinase, wortmannin-sensitive; PI4K-beta; PI4K92; PI4Kbeta; PI4KIII; PtdIns 4-kinase beta; type III phosphatidylinositol 4-kinase beta

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Gene Aliases: ESTM41; NPIK; PI4K-BETA; PI4K92; PI4KB; PI4KBETA; PI4KIIIBETA; PIK4CB

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UniProt ID: (Human) Q9UBF8, (Mouse) Q8BKC8, (Rat) O08561

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Entrez Gene ID: (Human) 5298, (Mouse) 107650, (Rat) 81747

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Function(s)

1-phosphatidylinositol 4-kinase activity protein binding ATP binding 14-3-3 protein binding nucleotide binding kinase activity transferase activity transferase activity, transferring phosphorus-containing groups phosphotransferase activity, alcohol group as acceptor

Process(es)

phosphatidylinositol biosynthetic process phosphorylation phosphatidylinositol phosphorylation phosphatidylinositol-mediated signaling receptor-mediated endocytosis signal transduction

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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PI4KB Polyclonal Antibody

PI4KB Antibody (13247-1-AP) in WB

Product Details

13247-1-AP

Western Blot (WB)

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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