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Invitrogen
PIBF1 Polyclonal Antibody
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PIBF1 Antibody (PA5-91916) in IHC (P)
Immunohistochemistry analysis of PIBF1 in paraffin-embedded human rectal cancer. Samples were incubated with PIBF1 Polyclonal antibody (Product # PA5-91916) using a dilution of 1:200 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Product Details
PA5-91916
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PIBF1 (Q8WXW3)
Conjugate
Form
Liquid
Concentration
0.46 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2806325
Product Specific Information
Positive Samples: Mouse heart; Cellular Location: Cytoplasm, Nucleus, centriolar satellite, centrosome, cytoskeleton, microtubule organizing center
Immunogen sequence: MSRKISKESK KVNISSSLES EDISLETTVP TDDISSSEER EGKVRITRQL IERKELLHNI QLLKIELSQK TMMIDNLKVD YLTKIEELEE KLNDALHQKQ
Target Information
Mediator of progesterone that by acting on the phospholipase A2 enzyme interferes with arachidonic acid metabolism, induces a Th2 biased immune response, and by controlling NK activity exerts an anti-abortive effect.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Centrosomal protein of 90 kDa; CEP90; PIBF; progesterone immunomodulatory binding factor 1; progesterone-induced blocking factor 1; Progesterone-induced-blocking factor 1; RP11-505F3.1
Gene Aliases: C13orf24; CEP90; PIBF; PIBF1; RGD1305077
UniProt ID: (Human) Q8WXW3
Entrez Gene ID: (Human) 10464, (Mouse) 52023, (Rat) 306104
biological_process
immune system process
mitotic metaphase plate congression
activation of JAK1 kinase activity
negative regulation of prostaglandin biosynthetic process
negative regulation of interleukin-12 production
positive regulation of interleukin-10 production
negative regulation of natural killer cell activation
nonmotile primary cilium assembly
negative regulation of tyrosine phosphorylation of Stat4 protein
positive regulation of tyrosine phosphorylation of Stat6 protein
protein localization to centrosome
mitotic spindle assembly
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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