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Product Details
PA5-65951
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human PIDD. Recombinant protein control fragment (Product #RP-106638).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2664826
Product Specific Information
Immunogen sequence: SFPVTPRGCSV TLACGVRLQF PAGATATPIT IRYRLLLPEP GLVPLGPHDA LLSHVLELQP HGVAFQQDVG LWLLFTPPQA RRCREVVV
Highest antigen sequence identity to the following orthologs - mouse 85%, rat 84%.
Target Information
The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp434D229; Leucine-rich repeat and death domain-containing protein; leucine-rich repeats and death domain containing; MGC16925; p53-induced death domain-containing protein 1; p53-induced protein with a death domain
Gene Aliases: LRDD; PIDD; PIDD1
UniProt ID: (Human) Q9HB75
Entrez Gene ID: (Human) 55367
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
cellular response to DNA damage stimulus
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
signal transduction
regulation of apoptotic process
positive regulation of apoptotic process
negative regulation of apoptotic process
positive regulation of NF-kappaB transcription factor activity
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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