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Product Details
PA5-96303
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-85 of human PIDD (NP_6658932)
Conjugate
Form
Liquid
Concentration
1.51 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2808105
Product Specific Information
Immunogen sequence: MAATVEGPEL EAAAAAGDAS EDSDAGSRAL PFLGGNRLSL DLYPGGCQQL LHLCVQQPLQ LLQVEFLRLS THEDPQLLEA TLAQL; Positive Samples: U-87MG, 293T, K-562, Mouse brain, Mouse liver, Mouse heart, Rat brain; Cellular Location: Cytoplasm, Nucleus
Target Information
The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp434D229; leucine-rich and death domain containing; Leucine-rich repeat and death domain-containing protein; leucine-rich repeats and death domain containing; MGC16925; p53 protein induced, with death domain; p53-induced death domain-containing protein 1; p53-induced protein with a death domain
Gene Aliases: 1200011D09Rik; AU042446; LRDD; PIDD; PIDD1
UniProt ID: (Human) Q9HB75, (Mouse) Q9ERV7
Entrez Gene ID: (Human) 55367, (Mouse) 57913, (Rat) 293625
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
cellular response to DNA damage stimulus
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
signal transduction
regulation of apoptotic process
positive regulation of apoptotic process
negative regulation of apoptotic process
positive regulation of NF-kappaB transcription factor activity
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
positive regulation of apoptotic signaling pathway
positive regulation of extrinsic apoptotic signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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