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PIGF Antibody (PA5-69078) in IHC (P)
Immunohistochemical analysis of PIGF in paraffin-embedded human bronchial epithelial tissue. Sample was probed with a PIGF polyclonal antibody (Product # PA5-69078) at a dilution of 1:100. Detection was performed with a donkey anti-Rabbit Cy3 secondary antibody at a dilution of 1:200. Images were taken at 20x magnification with an exposure time of 0.5-2.0 seconds.
Product Details
PA5-69078
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
synthetic peptide directed towards the N terminal region of human PIGF
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2688592
Product Specific Information
This target displays homology in the following species: Cow: 86%; Dog: 93%; Horse: 92%; Human: 100%; Mouse: 86%; Pig: 86%; Rat: 86%; Sheep: 86%
Target Information
Phosphatidylinositol-glycans(PIGs) aremulti-passtransmembrane proteins that localize to the endoplasmicreticulum. PIGs exhibitvariousfunctions but all are crucial for the biosynthesis of the glycosylphosphatidylinositol (GPI) anchor. Some PIG proteins are components of the GPI transamidase complex and play a role in the recognition of either the GPI attachmentsignal or the lipid portion of GPI. Other PIGs belong to the glycosyltransferase complex and function in the transfer of N-acetylglucosamine (GlcNAc) to phosphatidyli nositol (PI). A variety of other PIGs play distinct rolesin GPIsynthesis. PIG-F functions as an auxiliary subunit of ethanolamine phosphate (EtNP) transferases. It associates with PIG-O and isrequired for its expression and stability. Together these two PIGs function as an EtNP transferase and catalyze the transfer of EtNP to the third mannose (Man-3) of GPI. Amutation in the gene encoding PIG-F may result in a block of EtNP addition to Man-3 and lead to an absence of GPI-anchored proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GPI11 homolog; phosphatidylinositol glycan anchor biosynthesis, class F; Phosphatidylinositol-glycan biosynthesis class F protein; PIG-F
Gene Aliases: PIGF
UniProt ID: (Human) Q07326
Entrez Gene ID: (Human) 5281
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